Results 71 to 80 of about 240,870 (365)
Eastern Beringia and beyond: Late Wisconsinan and Holocene landscape dynamics along the Yukon Coastal Plain, Canada [PDF]
, 2012 Terrestrial permafrost archives along the Yukon Coastal Plain (northwest Canada) have recorded landscape development and environmental change since the Late Wisconsinan at the interface of unglaciated Beringia (i.e.
Fritz, Michael +6 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Evidence for suppressed mid-Holocene northeastern Australian monsoon variability from coral luminescence [PDF]
, 2014 Summer monsoon rainfall in northeastern (NE) Australia exhibits substantial interannual variability resulting in highly variable river flows. The occurrence and magnitude of these seasonal river flows are reliably recorded in modern inshore corals as ...
Cook, C.G. +6 more
core +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
A late Pleistocene long pollen record from Lake Urmia, NW Iran [PDF]
, 2008 A palynological study based on two 100-m long cores from Lake Urmia in northwestern Iran provides a vegetation record spanning 200 ka, the longest pollen record for the continental interior of the Near East.
Akhani, H +10 more
core +1 more source
Holocene impact craters on Earth
Miscellanea Geographica: Regional Studies on Development, 2023 Impact craters are formed by collisions of cosmic bodies moving with hypervelocity. The formation of these features is not restricted to the distant geological past; new structures are constantly being created and at least 13 confirmed impact craters and
Losiak Anna
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Post-disturbance vegetation dynamics during the Late Pleistocene and the Holocene: An example from NW Iberia [PDF]
, 2012 This is the post-print version of the final paper published in Global and Planetary Change. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Allen +67 more
core +2 more sources
Sedimentary Signatures of Persistent Subglacial Meltwater Drainage From Thwaites Glacier, Antarctica
Frontiers in Earth Science, 2022 Subglacial meltwater drainage can enhance localized melting along grounding zones and beneath the ice shelves of marine-terminating glaciers. Efforts to constrain the evolution of subglacial hydrology and the resulting influence on ice stability in space
A. P. Lepp +13 more
doaj +1 more source