Results 71 to 80 of about 89,718 (313)

Lateglacial and early holocene environmental changes along the Northwest European continental margin [PDF]

open access: yes, 2005
Palynological studies from two lacustrine sites, Lochan An Druim in northern Scotland and NikkupierjaVri in northern Finnmark, have demonstrated quantitative changes in the vegetation of the northwest European continental margin, following deglaciation ...
Ranner, Patricia Helen
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Holocene coastal changes in Rio de Janeiro state, Brazil [PDF]

open access: yes, 1988
Evidence of Holocene sea-level changes along the Rio de Janeiro State Coast, and for the evolution of coastal lagoons and barriers in response to these sea- level movements, has been examined using stratigraphical and micropalaeontological techniques ...
Ireland, Stephen, Ireland, S
core  

An Aegean History and Archaeology Written through Radiocarbon Dates

open access: yesJournal of Open Archaeology Data, 2020
This dataset is the outcome of an INSTAP-funded project “An Aegean Prehistory Written in Radiocarbon Dates”. It includes 3159 14C dates from 353 sites in Greece and reflects an attempt to exhaustively collect and cross-check all published radiocarbon ...
Markos Katsianis   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pola Adaptasi Penghuni Gua Budaya Toala

open access: yesBerkala Arkeologi, 1993
Kehidupan penghuni gua Budaya Toala berlangsung sejak Kala Pasca Plestosen hingga awal masehi. Kehidupan Budaya Toala ini berlangsung cukup lama dan mampu bertahan beratus-ratus tahun lamanya.
Indah Asikin Nurani
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Between desert and forest: the Holocene savannas of NE-Nigeria

open access: yes, 2006
Numerous ecologists postulate that West African savannas are mostly the result of degradation of formerly closed forests. This hypothesis can only be tested by palaeoecological investigations.
Salzmann, Ulrich
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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