Results 81 to 90 of about 240,870 (365)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Testate amoebae as a proxy for reconstructing Holocene water table dynamics in southern Patagonian peat bogs [PDF]

, 2014
Funded by Natural Environment Research Council. Grant Numbers: NE/I022809/1, NE/I022981/1, NE/I022833/1, NE/I023104/1 Ricardo Muza and the Wildlife Conservation Society Karukinka Park Acknowledgements This work was supported by the Natural Environment ...
Aaby, Adema, Amesbury, Barber, Barber, Bobrov, Booth, Booth, Booth, Borromei, Charman, Charman, Charman, Charman, Charman, Charman, Daley, Daley, De Vleeschouwer, Deflandre, Foissner, Fritz, Garreaud, Gomaa, Heal, Heger, Hendon, Hendon, Juggins, Kleinebecker, Lamarre, Lamarre, Lamentowicz, Lamentowicz, Lamy, Loisel, Loisel, Mauquoy, Mauquoy, Mauquoy, Mitchell, Mitchell, Moschen, Payne, Payne, Payne, Payne, Payne, Payne, Pendall, Qin, R Core Team, Roland, Schoning, Schouten, Smith, Smith, Stanek, Sullivan, Swindles, Telford, Telford, Ter Braak, Ter Braak, Tonello, Turner, van Bellen, Warner, Wilmshurst, Yu   +69 more
core   +1 more source

Holocene evolution of the coast of Holland

Marine Geology, 1992
Abstract The Holocene evolution of the coast of Holland was controlled by the complex interaction of such diverse parameters as wave and tidal climate, the rate of sea-level rise, and the morphology of the pre-transgressional surface. The latter, in combination with the rate of sea-level rise, mainly determines the location of sediments sources and ...
Beets, D.J. (author), Van der Valk, L. (author), Stive, M.J.F. (author)   +2 more
openaire   +4 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Recent origin of low trabecular bone density in modern humans [PDF]

, 2014
Humans are unique, compared with our closest living relatives (chimpanzees) and early fossil hominins, in having an enlarged body size and lower limb joint surfaces in combination with a relatively gracile skeleton (i.e., lower bone mass for our body ...
Bernhard Zipfel, Brian G. Richmond, Christopher B. Ruff, Cowgill, Eaton, Habiba Chirchir, Jean-Jacques Hublin, Kristian J. Carlson, Ruff, Ruff, Tracy L. Kivell, Trinkaus   +11 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Floodplain environmental change during the younger dryas and holocene: Evidence from the lower kennet valley, south central England [PDF]

, 2006
Many lowland rivers across northwest Europe exhibit broadly similar behavioural responses to glacial-interglacial transitions and landscape development. Difficulties exist in assessing these, largely because the evidence from many rivers remains limited
Collins, PEF, Fenwick, IM, Keith-Lucas, DM, Worsley, P   +3 more
core  

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Local extinctions in the small mammal's assemblages between late Holocene and historical times in Talagapa mountains (Patagonia, Argentina): The role of land use changes [PDF]

, 2016
The aim of this work was to evaluate possible changes in the small mammal composition in the Patagonian arid Extra-Andean steppes between the late Holocene and historical times.
Andrade, Analia, Monjeau, Jorge Adrian
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source