Results 121 to 130 of about 58,381 (260)
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims To examine the association between branched‐chain α‐keto acids (BCKAs) and pancreatic steatosis in patients with type 2 diabetes (T2DM). Methods This cross‐sectional study was conducted from January 2023 to March 2025. Upper abdominal computerized tomography was performed, pancreatic volume (PV), PV index (PVI), CT attenuation of pancreas
Jie Gao +9 more
wiley +1 more source
Genetic basis of Asian diabetes
Journal of Diabetes Investigation, EarlyView.ABSTRACT Recent genomic studies in Asian populations have advanced our understanding of the diagnosis, pathophysiology, risk prediction, and precision care of diabetes. Monogenic diabetes, including maturity‐onset diabetes of the young (MODY) and mitochondrial diabetes, highlights the importance of genetic diagnosis for subtype‐specific care.
Takafumi Ojima, Toshimasa Yamauchi
wiley +1 more source
Journal of Diabetes Investigation, EarlyView.Circulating Annexin A2 is positively associated with peripheral insulin sensitivity. ABSTRACT Background and Aim Subcellular annexin A2 (ANXA2) is known to regulate membrane dynamics and GLUT4 trafficking in adipocytes; however, the role of serum ANXA2 in glucose metabolism remains unclear.
Yuichi Ito +12 more
wiley +1 more source
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims This study evaluated the clinical utility of circulating miR‐342‐3p for diagnosing gestational diabetes mellitus (GDM) and predicting adverse perinatal outcomes (APOs). Methods A retrospective cohort of 261 GDM women (the GDM group) and 261 propensity score‐matched healthy controls (the Normal group) was analyzed.
Kangjun Yu, Sanqiang Niu, Hai Liang
wiley +1 more source
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims We investigated the characteristics of typical adult‐onset type 1 diabetes (T1D) and insulin‐dependent latent autoimmune diabetes in adults (LADA) in Thailand. Methods This retrospective chart review enrolled typical T1D and insulin‐dependent LADA patients diagnosed at age ≥30 years, and who were followed up at Siriraj Hospital, Thailand,
Chanoknan Luksameejaroenchai +2 more
wiley +1 more source
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims This study aimed to examine the associations of maternal first‐trimester atherogenic index of plasma (AIP) with gestational diabetes mellitus (GDM) and birth weight outcomes, and the mediating role of second‐trimester blood glucose. Methods This prospective cohort study included 5,706 pregnant women without pre‐existing diabetes or other ...
Doudou Zhao +8 more
wiley +1 more source
Fasting proinsulin as a predictor of future glucose tolerance deterioration in Japanese adults
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims/Introduction Proinsulin is associated with β‐cell stress and has been linked to subsequent deterioration in glucose metabolism in Western populations, but its predictive value in Asian populations remains unclear. We investigated whether proinsulin is associated with future glucose tolerance deterioration in community‐dwelling Japanese ...
Nobuhiro Kajihara +6 more
wiley +1 more source
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims Weight loss by laparoscopic sleeve gastrectomy (LSG) compared to medical weight loss (low‐calorie diet: LCD) ameliorates diabetes and metabolic dysfunction‐associated steatotic liver disease (MASLD). We aimed to evaluate changes in liver pathology 1‐year after LSG and their associations with metabolic factors in Japanese participants with
Daiki Matsubara +11 more
wiley +1 more source
The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases
Journal of Periodontal Research, EarlyView.This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur +3 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet +8 more
wiley +1 more source