Results 121 to 130 of about 55,747 (257)

Continuous glucose monitoring–guided management of capivasertib‐associated hyperglycemia: A case series of three patients

Journal of Diabetes Investigation, EarlyView.
Continuous glucose monitoring (CGM) visualized cyclic glycemic fluctuations associated with the 4‐days‐on/3‐days‐off capivasertib schedule. Compared with off‐treatment days, dosing days showed higher mean sensor glucose, greater coefficient of variation (CV), more time above 250 mg/dL, and lower time in range (TIR; 70–180 mg/dL).
Hiroki Okumura, Ryotaro Bouchi, Kenju Ando, Hannah Mizuno, Hirofumi Sugimoto, Kotaro Umamoto, Noriko Kodani, Noriko Ihana‐Sugiyama, Kazuo Izumi, Mitsuru Ohsugi, Kohjiro Ueki, Akihiko Shimomura, Chikako Shimizu, Akiyo Tanabe   +13 more
wiley   +1 more source

Associations of finerenone with reduced insulin resistance in patients with type 2 diabetes and chronic kidney disease: A real‐world observational study

Journal of Diabetes Investigation, EarlyView.
This real‐world observational study enrolled 256 patients with type 2 diabetes and chronic kidney disease (T2D‐CKD). After 12 months of finerenone treatment, 45 patients completed follow‐up. Finerenone was associated with significant improvements in insulin resistance markers (HOMA‐IR, TyG index), lipid profile (LDL‐C), glycemic control (HbA1c), and ...
Xin Zhao, Bohan Liu, Ran Sun, Yaxuan Shi, Ya Liu   +4 more
wiley   +1 more source

Assessing the Diagnostic Performance of Triglyceride–Glucose–Based Indices for Early Detection of Metabolic Syndrome in Paediatric Down Syndrome

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Down syndrome (DS) youth have an increased risk of metabolic syndrome (MetS). This study assessed the diagnostic performance of the triglyceride–glucose index (TyG) and its derivatives—TyG‐BMI, TyG‐waist circumference (WC) and TyG‐waist‐to‐height ratio (WHtR) in detecting MetS compared with traditional markers.
Valeria Calcaterra, Lucia Labati, Alessandra Anna Gazzarri, Alice De Lorenzo, Ilaria Anna Maria Scavone, Gianvincenzo Zuccotti   +5 more
wiley   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

The ALT/AST Ratio as a Predictor of MASLD in Obese Children: A Comparative Analysis with Metabolic Indices Including HOMA-IR and TyG. [PDF]

J Clin Med
Kabukçu HO, Hazer İ.
europepmc   +1 more source

Associations Between Body Composition and Metabolic Health in Children With Obesity

Maternal &Child Nutrition, EarlyView.
ABSTRACT Childhood obesity is an increasing public health problem with heterogeneous metabolic health outcomes. In children, distinguishing differences in body composition between individuals with metabolically healthy obesity (MHO) and those with metabolic syndrome (MS) may be useful for understanding the impact of body composition on metabolic health.
Desiree Lopez‐Gonzalez, Patricia Clark, Nayely Garibay‐Nieto, Pamela Reyes‐Delpech, Rodolfo Pérez, America Miranda‐Lora   +5 more
wiley   +1 more source

Relationship of HOMA-IR with chronic kidney disease in diabetic and non-diabetic Chinese populations: findings from the REACTION study. [PDF]

Front Endocrinol (Lausanne)
Liao Y, Guan M, Wan Q, Song H, Hu H.
europepmc   +1 more source

HOMA-IR Anomalies and Sugar Consumption in Young with Euglycemia

Pakistan Journal of Nutrition, 2015
Juan Manuel Munoz Cano, Juan Cordova Hernandez, Xavier Boldo Leon, David del Valle Laveaga   +3 more
openaire   +1 more source

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction–Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole‐Body Fat Metabolism, and Organ‐Specific Lipid Deposition

Obesity Reviews, EarlyView.
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson, Martin Whyte, Alex E. Henney, Uazman Alam, Louise Goff, Barbara A. Fielding, A. Margot Umpleby   +6 more
wiley   +1 more source

The combined impact of time in range and HOMA-IR on neonatal outcomes in gestational diabetes mellitus: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Chen M, Sun J, Yang J, Wang J, Shu C, Zhang L, Chai X, Dong Y.   +7 more
europepmc   +1 more source