Results 111 to 120 of about 58,381 (260)

Oral Health Interventions for People Living With Diabetes From a Public Health Perspective: A Mapping Review

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives Despite growing concerns about the oral health‐diabetes link, there is a lack of dental health interventions focused on people with diabetes. This mapping review synthesised the current landscape of oral health interventions for people with diabetes and identified future opportunities.
Fernando Valentim Bitencourt   +8 more
wiley   +1 more source

Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua   +8 more
wiley   +1 more source

Multisystem developmental abnormalities and insulin resistance in ADTKD‐HNF1B with the p.E105K variant: A clinical conundrum

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang   +5 more
wiley   +1 more source

Associations between prior wasting malnutrition and indices of insulin secretion and sensitivity among six cohorts from Asia and Africa: The SAMPA study

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims The role of prior wasting malnutrition (PM) in determining insulin sensitivity and secretion in low‐ and middle‐income countries (LMICs) remains unclear. We investigated associations of insulin indices with PM and whether these were modified by current body mass index (BMI).
Sharon E. Cox   +19 more
wiley   +1 more source

The efficacy of interventions to prevent type 2 diabetes among women with recent gestational diabetes mellitus—First update of a living systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Introduction The increased risk of developing type 2 diabetes mellitus (T2DM) in the decade following childbirth among women with gestational diabetes mellitus (GDM) warrants early intervention. A prespecified update of a systematic review and meta‐analyses published in 2024 was performed, examining the efficacy of interventions to prevent ...
Vivian Y. J. Lee   +12 more
wiley   +1 more source

OGTT‐Derived β‐Cell Function–Based Stratification of 2‐Year Glycaemic Transitions in Chinese Adults With Prediabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Prediabetes is heterogeneous, with variable progression to diabetes or reversion to normoglycemia. We evaluated whether the insulin secretion‐sensitivity index‐2 (ISSI‐2), an oral glucose tolerance test (OGTT)‐derived integrated surrogate of β‐cell function relative to insulin sensitivity and prevailing glycemia, was associated with ...
Yuntong Liu   +13 more
wiley   +1 more source

A 52‐Week Efficacy and Safety Study of Teneligliptin, as an Add‐On to Empagliflozin and Metformin in Patients With Type 2 Diabetes Mellitus: A Randomised, Double‐Blind, Placebo‐Controlled Phase 3 Trial (TERA305 Study)

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the long‐term efficacy and safety of teneligliptin add‐on in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin. Materials and Methods In this randomised, double‐blind, phase 3 trial, 214 patients received teneligliptin 20 mg (n = 107) or placebo (n = 107) once daily for 24 ...
Jun Sung Moon   +14 more
wiley   +1 more source

Role of HOMA-IR on Breast Cancer Women

open access: yesCancer Therapy & Oncology International Journal, 2021
openaire   +1 more source

Liver Fibrosis and IRS1 rs2972146 Are Associated With Weight Loss Response After Metabolic Bariatric Surgery

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background and Aims Weight loss after metabolic bariatric surgery (MBS) is heterogeneous, and the contribution of liver histology and genetic susceptibility to insufficient weight loss (IWL) or weight regain (WR) remains unclear. We assessed the prevalence of IWL and WR after MBS and their association with liver histology and metabolic ...
Felice Cinque   +18 more
wiley   +1 more source

Reduced IFN-γ-expressing SARS-CoV-2 specific CD4+ T cells and transient CD8 + T cell activation associate with higher HOMA-IR 1-year post COVID-19 in obese individuals

open access: yesScientific Reports
Insulin resistance is one of the metabolic complications of COVID-19. Our previous study showed a 22% median increase in homeostasis model assessment-estimated insulin resistance (HOMA-IR) in obese individuals at 12 months post-infection compared to ...
Rona Kartika   +7 more
doaj   +1 more source

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