Results 111 to 120 of about 55,747 (257)

HOMA-IR Values in Overweight and Obesity Subjects With and Without Sarcopenia

F1000Research
Introduction Obesity and overweight, a state of subclinical inflammation, and sarcopenia, the age-related loss of muscle mass and function, are interrelated conditions. Insulin resistance is a key metabolic dysfunction linking both.
Feryandi Limanto Suhardi, Andi Makbul Aman, Agus Sudarso, Syakib Bakri, Haerani Rasyid, Arifin Seweng   +5 more
openaire   +1 more source

Subgroups of Adult‐Onset Diabetes: A Prospective Follow‐Up Study of Progression of Insulin Resistance and Deficiency and Association With Liver Steatosis and Fibrosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess progression of insulin deficiency and resistance in diabetes, the stability of cluster‐based subgrouping, and the association between steatotic liver disease (SLD), liver fibrosis (LF), and tissue insulin resistance. Materials and Methods Participants from a regional diabetes register were studied within 3 years from diagnosis ...
Aleksi Laitinen, Annemari Käräjämäki, Aki J. Käräjämäki, Samu Kurki, Liisa Hakaste, Olof Asplund, Johan Hultman, Kaj Lahti, Mikko Lehtovirta, Emma Ahlqvist, Tiinamaija Tuomi   +10 more
wiley   +1 more source

Aerobic Exercise Training Increases Circulating sRAGE in Adults With Type 2 Diabetes: Associations With Sheddase Regulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins, Corey E. Mazo, James Shadiow, Pallavi Varshney, Edwin R. Miranda, Victoria R. Miranda, Maggie Eisenberg, Jane E. Nakamura, Elif A. Oral, Jacob M. Haus   +9 more
wiley   +1 more source

Triple combination cystic fibrosis transmembrane receptor modulator effects on glycaemia and insulin kinetics in cystic fibrosis with and without diabetes

Internal Medicine Journal, EarlyView.
Abstract Background Greater insight into the effects of cystic fibrosis (CF) transmembrane modulators such as elexacaftor‐tezacaftor‐ivacaftor (ETI) on glucose metabolism can support a more dynamic and individualised approach to CF‐related dysglycaemia.
Yi W. Chen, Rachel Prasad, Peter G. Middleton, D. Jane Holmes‐Walker   +3 more
wiley   +1 more source

Time in range during caloric restriction in type 2 diabetes with obesity

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction To evaluate glycemic changes during caloric restriction with continuous glucose monitoring (CGM)‐derived time in range (TIR) in individuals with type 2 diabetes and obesity. Materials and Methods This 12‐week single‐arm intervention consisted of 6 weeks of home‐delivered meals (800–1,200 kcal/day), followed by 6 weeks of self ...
Jinyoung Kim, Joonyub Lee, Mee Kyoung Kim, Oakkee Hong, Young Na, Su‐Jeong Park, Yoon‐Ju Song, Ki‐Hyun Baek, Ki‐Ho Song, Hyuk‐Sang Kwon   +9 more
wiley   +1 more source

Role of HOMA-IR on Breast Cancer Women

Cancer Therapy & Oncology International Journal, 2021
openaire   +1 more source

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma, Takahiro Tsutsumi, Asako Miyazaki, Kyoichiro Tsuchiya   +3 more
wiley   +1 more source

Elevated serum galectin‐3 levels predict the incidence of type 2 diabetes mellitus in a Japanese general population: A 10‐year follow‐up study

Journal of Diabetes Investigation, EarlyView.
Elevated serum galectin‐3 levels are associated with the incidence of T2DM independent of insulin resistance, particularly among non‐obese individuals. There may be a diabetogenic mechanism that is not mediated by obesity or insulin resistance. ABSTRACT Aims/Introduction Although several studies have reported elevated serum galectin‐3 levels in type 2 ...
Harumi Takubo‐Yoshimura, Mika Enomoto, Ako Fukami, Nagisa Morikawa, Yume Nohara‐Shitama, Hiromi Sato, Mayo Shimoyama‐Yamamoto, Hisashi Adachi, Yoshihiro Fukumoto   +8 more
wiley   +1 more source

Relative contributions of basal vs postprandial hyperglycaemia to overall glycaemic control in newly diagnosed Chinese adults with type 2 diabetes before and after 3 months' intensive glucose‐lowering therapy

Journal of Diabetes Investigation, EarlyView.
In newly‐diagnosed Chinese with T2D, Contribution of basal hyperglycaemia to hyperglycaemic exposure decreased substantially and the relative importance of postprandial hyperglycaemia increased markedly after 3 months glucose‐lowering therapy. Therapy should be re‐evaluated after initial treatment, and that a greater focus on limiting postprandial ...
Yixuan Sun, Yong Luo, Cong Xie, Karen L. Jones, Michael Horowitz, Christopher K. Rayner, Jianhua Ma, Tongzhi Wu   +7 more
wiley   +1 more source

Taiwanese consensus statement on the use of diabetes‐specific formula: Scientific evidence

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction Medical Nutrition Therapy remains the cornerstone of diabetes management. Clinical evidence shows that early intervention with medical nutrition therapy can significantly improve cardiometabolic markers, thereby delaying or preventing diabetes‐related complications.
Chih‐Hsun Chu, Hui‐Yu Peng, Chun‐Chuan Lee, Chih‐Yuan Wang, Yuh‐Jane Ko, Wen‐Hui Chen, Pi‐Hui Hsu, Chien‐Ning Huang, Yi‐Sun Yang, Kuei‐Mei Yeh, Chung‐Mei Ouyang, Horng‐Yih Ou   +11 more
wiley   +1 more source