Results 91 to 100 of about 58,381 (260)

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Joint association of weight-adjusted-waist index and physical activity with insulin resistance in adolescents: a cross-sectional study

BMC Endocrine Disorders
Background The weight-adjusted waist index (WWI) is a recently developed obesity metric, and the aim of this study was to investigate the relationship between physical activity (PA) and WWI and the homeostasis model assessment of insulin resistance (HOMA-
Yong Zhou, Peng Tang, Yican Wang, Ying Tang, Yujian Yang   +4 more
doaj   +1 more source

Evaluation of waist-to-height ratio as a predictor of insulin resistance in non-diabetic obese individuals. A cross-sectional study

São Paulo Medical Journal, 2017
BACKGROUND: Insulin resistance (IR) and progressive pancreatic β-cell dysfunction have been identified as the two fundamental features in the pathogenesis of obesity and non-insulin-dependent diabetes mellitus.
Giovana Jamar, Flávio Rossi de Almeida, Antonio Gagliardi, Marianna Ribeiro Sobral, Chao Tsai Ping, Evandro Sperandio, Marcelo Romiti, Rodolfo Arantes, Victor Zuniga Dourado   +8 more
doaj   +1 more source

Dietary Flavonoid Hyperoside Ameliorates High‐Fat Diet‐Induced Type 2 Diabetes Mellitus by Enhancing Brown Adipose Tissue Thermogenesis, White Adipose Tissue Browning, and Gut Microbiota Remodeling

Phytotherapy Research, EarlyView.
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai, WenXin Zeng, Yu Luo, Qiang Liu, CuiPing Jiang, YanKui Yi, JieYu Chen, ChunYan Shen   +7 more
wiley   +1 more source

INSULIN RESISTANCE REDUCTION AFTER SUSTAINED VIROLOGICAL RESPONSE WITH DIRECT ACTING ANTIVIRAL:NOT EVERY POPULATION IMPROVES

Arquivos de Gastroenterologia
BACKGROUND: Hepatitis C virus (HCV) infection is a serious public health problem, that affects approximately 170 million people worldwide. Chronic HCV infection is associated with hepatic insulin resistance and an increased risk of diabetes HCV-infected
Vanessa Gutierrez de ANDRADE, Fábio da Silva YAMASHIRO, Cássio Vieira OLIVEIRA, Alecsandro MOREIRA, Fernanda Cristina WINCKLER, Giovanni Faria SILVA   +5 more
doaj   +1 more source

The Cut-off Value of Blood Mercury Concentration in Relation to Insulin Resistance

Journal of Obesity & Metabolic Syndrome, 2017
Background : Increased blood mercury concentration is associated with inflammation, and chronic inflammation can cause insulin resistance. We examined the cut-off value of blood mercury in relation to an increased score on the homeostasis model ...
Seok-Hoon Lee, Beomhee Choi, Soo-Jung Park, Young-Sang Kim, Nam-Seok Joo   +4 more
doaj   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

The effect of measurement uncertainty for HOMA-IR in assessment of insulin resistance

Medicine Science, 2019
In this study, it is aimed to estimate not just the uncertainty measurement for the parameters of glucose and insulin having role when calculating HOMA-IR, but also true positiveness and negativeness in terms of cut-off values.
Mujgan Ercan, Aysen Caniklioglu, Esra Firat Oguz, Cigdem Yucel, Mehmet Ozcan, Fatma Meric Yilmaz, Sedat Abusoglu, Canan Topcuoglu, Yusuf Bayrakceken   +8 more
doaj   +1 more source