Results 81 to 90 of about 58,381 (260)

The HOMA-Adiponectin (HOMA-AD) Closely Mirrors the HOMA-IR Index in the Screening of Insulin Resistance in the Brazilian Metabolic Syndrome Study (BRAMS).

PLoS ONE, 2016
BackgroundThe major adverse consequences of obesity are associated with the development of insulin resistance (IR) and adiposopathy. The Homeostasis Model Assessment-Adiponectin (HOMA-AD) was proposed as a modified version of the HOMA1-IR, which ...
Brunna Sullara Vilela, Ana Carolina Junqueira Vasques, Roberta Soares Lara Cassani, Adriana Costa E Forti, José Carlos Pareja, Marcos Antonio Tambascia, BRAMS Investigators, Bruno Geloneze   +7 more
doaj   +1 more source

Association of insulin resistance with polymorphic variants of Clock and Bmal1 genes: A case–control study

Clinical and Experimental Hypertension, 2020
Background: Little information is available in the literature for the correlation of insulin resistance (IR) and CLOCK gene polymorphism in Chinese population.
Gui-Yang Li, Huan Wang, Hui Chen
doaj   +1 more source

Cardiometabolic Biomarkers for Disease Severity Prediction in Metabolic Dysfunction‐Associated Steatotic Liver Disease

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The impacts of cardiometabolic risk factors (CMRFs) and the biomarkers on disease severity in metabolic dysfunction‐associated steatotic liver disease (MASLD) remain elusive. Accordingly, a multicenter study by recruiting MASLD patients from a nationwide registry database was conducted with a total of 2882 MASLD patients (54.1% males, mean age 
Jee‐Fu Huang, Chi‐Yi Chen, Ming‐Jong Bair, Tzu‐Chun Lin, Ming‐Lun Yeh, Pei‐Chien Tsai, Yu‐Ju Wei, Chih‐Wen Wang, Po‐Chen Liang, Ming‐Yen Hsieh, Mei‐Hsuan Lee, Chia‐Yen Dai, Chung‐Feng Huang, Ming‐Lung Yu, Wan‐Long Chuang   +14 more
wiley   +1 more source

Metabolic Syndrome and Dementia Risk in Older Adults: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Dementia is a major global health issue in aging societies. Metabolic syndrome (MetS), a cluster of metabolic abnormalities, has been proposed as a modifiable risk factor for dementia, although existing evidence remains inconsistent. This review examined recent studies on the association between MetS and dementia risk in older adults.
Hyojin Park, Mallika Chuansangeam, Yuan‐Han Yang   +2 more
wiley   +1 more source

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, EarlyView.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity

Obesity, EarlyView.
ABSTRACT Objective This study aimed to investigate the effects of breaking up sedentary behavior (SB) on daily movement behavior and energy balance in adults with overweight/obesity. Methods Thirty participants (16F/14M; 34.2 ± 7.3 years; 29.5 ± 3.2 kg/m2) were randomized to either BREAK (multiple 5‐min brisk walking bouts) or a duration‐matched ...
Heloisa C. Santo Andre, Elisa Le Roux, Nathan P. De Jong, Patricia R. Smith, Andrew H. Lange, Carlos Mendez, Alexandre Zahariev, Melissa L. Mamele, Ginger Johnson, Zhaoxing Pan, Chantal Simon, Daniel H. Bessesen, Ana J. Pinto, Audrey Bergouignan   +13 more
wiley   +1 more source

Optimal cutoffs of HOMA-IR and HOMA-B and Diagnostic Performance of Predictors for Post-Transplant Diabetes Mellitus

Indian Journal of Transplantation
Background: Diabetes mellitus occurs in a substantial number of patients following renal transplantation. The presence of Insulin resistance in diabetics can be assessed by the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the ...
Anish G Kumar, V. Narayanan Unni, Bipi K Prasannan, Vipin Valam Puthussery   +3 more
doaj   +1 more source

Can Visceral Adiposity Index Serve as a Simple Tool for Identifying Individuals with Insulin Resistance in Daily Clinical Practice?

Medicina, 2019
Background and objectives: The visceral adiposity index (VAI), estimating visceral adiposity dysfunction through a simple formula, could serve as a useful tool for identifying individuals at higher cardiometabolic risk.
Ladislav Štěpánek, Dagmar Horáková, Ľubica Cibičková, Helena Vaverková, David Karásek, Marie Nakládalová, Jana Zapletalová   +6 more
doaj   +1 more source

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

Obesity, EarlyView.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi, Celeste Lauriola, Cristina Caccioppoli, Rossella D'Oria, Nicola Marrano, Giuseppina Biondi, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino, Angelo Cignarelli   +10 more
wiley   +1 more source

Cross-sectional comparison of the association between three different insulin resistance surrogates and frailty: NHANES 1999-2018

Frontiers in Endocrinology
BackgroundThe correlation between various insulin resistance surrogates and frailty remains under investigation in the scientific community.MethodsData from NHANES (1999-2018) were used.
Tianjie Lai, Fenglei Guan, Yunxian Chen, Konghe Hu   +3 more
doaj   +1 more source