Results 71 to 80 of about 58,381 (260)

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Insulin Resistance and Hyperinsulinemia in Patients with Chronic Liver Disease and Hepatocellular Carcinoma

Clinical Medicine Insights: Endocrinology and Diabetes, 2009
Objectives To investigate the role of insulin resistance (IR) and insulin plasma levels (IRI) in patients with chronic liver disease (CLD) and hepatocellular carcinoma (HCC).
Valter Donadon, Massimiliano Balbi, Antonio Perciaccante, Pietro Casarin, Giorgio Zanette   +4 more
doaj   +1 more source

Study of beta-cell function (by HOMA model) in metabolic syndrome

Indian Journal of Endocrinology and Metabolism, 2011
Introduction: The clustering of cardiovascular risk factors is termed the metabolic syndrome (MS), which strongly predict risk of diabetes and cardiovascular disease.
M K Garg, M K Dutta, Namita Mahalle
doaj   +1 more source

Association between triglyceride glucose index and atherosclerotic plaques and Burden: findings from a community-based study

Cardiovascular Diabetology, 2022
Background Insulin resistance is an important cause of cardiovascular events and cerebral infarction development. We aimed to investigate the association of the triglyceride glucose (TyG) index with atherosclerotic burden and plaques in coronary, intra ...
Mengxing Wang, Lerong Mei, Aoming Jin, Xueli Cai, Jing Jing, Suying Wang, Xia Meng, Shan Li, Tiemin Wei, Yongjun Wang, Yuesong Pan   +10 more
doaj   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Machine Learning–Based Comparative Analysis of Blood Cell–Derived Inflammatory Indices for Predicting MAFLD and Liver Fibrosis: Evidence From NHANES 2017–2020

Journal of Clinical Laboratory Analysis, EarlyView.
This research assesses the correlations and diagnostic efficacy of blood cell‐derived inflammatory indicators in predicting metabolic dysfunction‐associated fatty liver disease (MAFLD) and liver fibrosis using NHANES 2017–2020 data. AISI had the highest predictive capability for MAFLD, while PLR served as the most efficacious indicator for fibrosis ...
Hao Chen, Qinmei Chen, Xiangqian Wang, Yixian He, Xiqiao Zhou   +4 more
wiley   +1 more source

HOMA-IR as a Predictor of PAI-1 Levels in Women with Severe Obesity. [PDF]

Biomedicines
Background: Obesity is a chronic inflammatory disorder that increases the risk of cardiovascular diseases (CVDs). Given the high CVD mortality rate among individuals with obesity, early screening should be considered. Plasminogen activator inhibitor (PAI-1), a cytokine that links obesity and CVDs, represents a promising biomarker. However, PAI-1 is not
Martins Kattah F, Janjusevic M, Figueiredo N, Santos Oliveira E, Carielo Lima G, Dâmaso AR, Oyama LM, Fluca AL, de Melo PRE, Aderuza Horst M, Aleksova A, Campos Corgosinho F.   +11 more
europepmc   +5 more sources

Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Type 2 diabetes (T2DM) heightens cognitive impairment risk, yet the mechanisms remain unclear. Hyperglycemia‐induced iron dysregulation in deep gray matter (DGM) nuclei may be a crucial mechanism. Purpose To investigate DGM iron deposition in T2DM using Quantitative Susceptibility Mapping (QSM) and determine its association with ...
Kun Wang, Jiahe Wang, Ziyu Diao, Xin Tan, Shijun Qiu, Jie An   +5 more
wiley   +1 more source

High-molecular weight adiponectin/HOMA-IR ratio as a biomarker of metabolic syndrome in urban multiethnic Brazilian subjects.

PLoS ONE, 2017
Metabolic syndrome (MetS) has an important epidemiological relevance due to its increasing prevalence and association with type 2 diabetes and cardiovascular disease. Insulin resistance is a core feature of the MetS.
Virgínia Genelhu de Abreu, Cyro José de Moraes Martins, Patricia Aguiar Cardoso de Oliveira, Emilio Antonio Francischetti   +3 more
doaj   +1 more source

Association Between Triglyceride‐Glucose Index and in‐Hospital Intensive Care Unit Readmission in Ischemic Stroke Patients: A Retrospective Analysis Based on the MIMIC‐IV Database

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study utilized the Medical Information Mart for Intensive Care database to investigate the association between the triglyceride–glucose (TyG) index and in‐hospital intensive care unit (ICU) readmission in patients with ischemic stroke (IS). Among 2929 patients, 24.0% experienced ICU readmission.
Di Zhang, Ying‐Lun Chen, Jian Zhang, Xiang‐Jun Hu   +3 more
wiley   +1 more source