Results 101 to 110 of about 9,824,702 (297)

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Validating Bioanalytical Methods for Biomarker Quantitation: A Regulatory Document Review

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Biomarkers are used to assess normal physiological processes in the body; to diagnose and select therapy for various diseases; and to develop new drugs. The increasing use of biomarkers as drug development tools necessitates improvements in
V. M. Kosman, M. V. Karlina, N. M. Faustova, M. N. Makarova, V. G. Makarov   +4 more
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Ketoprofen Comparative Pharmacokinetics Analysis in Humans and Animals: A Review

Безопасность и риск фармакотерапии
INTRODUCTION. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) with pronounced analgesic, anti-inflammatory and antipyretic effect. Ketoprofen pharmacokinetics is comparatively well described in various in vivo models. Since it is potentially
E. M. Petrova, V. M. Kosman, M. V. Karlina, M. N. Makarova, V. G. Makarov   +4 more
doaj   +1 more source

Securing Our Future Homes: Smart Home Security Issues and Solutions [PDF]

, 2019
The Internet of Things, commonly known as IoT, is a new technology transforming businesses, individuals’ daily lives and the operation of entire countries.
Romano, Nicholas
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Study of the Safety and Toxicokinetic Parameters of the Drug Eladis® in Preclinical Trials with Repeated Administration

Антибиотики и Химиотерапия
Cough is one of the most common reasons for initial visits to healthcare providers, affecting 40–50% of patients with viral respiratory tract infections.
A. A. Matichin, M. V. Miroshnikov, A. A. Matichina, V. M. Kosman, M. V. Karlina, E. M. Petrova, A. A. Globenko, E. A. Jain, A. V. Kapashin, A. L. Vladykin, A. S. Kolosov, M. A. Pasko   +11 more
doaj   +1 more source

HIV and orientation of subsistence and commercial home gardens in rural Ghana: Crop composition, crop diversity and food security [PDF]

, 2010
An empirical study was conducted to explore differences and similarities in biodiversity in subsistence and commercial home gardens of HIV-positive and HIV-negative rural households in the Eastern Region of Ghana and their significance in household food ...
Akrofi, S., Price, L.L., Struik, P.C.
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Home Health Aides [PDF]

, 2010
Home health aides typically work for certified home health or hospice agencies that receive government funding and therefore must comply with extensive regulations.
Maye, Chenoa
core   +1 more source