Results 41 to 50 of about 8,076,960 (292)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
24 maalausta sekunnissa: Eino Ruutsalon taiteen uusi ulottuvuus 1960-luvun alussa
Tahiti, 2017 Artikkelissani haen vastausta kysymykseen, miksi Eino Ruutsalo (1921–2001) lopetti vuonna 1961 moneksi vuodeksi maalaamisen kankaalle ja ryhtyi maalaamaan filmille.
Marko Home
doaj
Kulturella Perspektiv, 2006 In this article, the process of urban migration and what is considered "home" for migrants in Bolivia is discussed. I explore the meaning of "home" as a sense of belonging and identification connected to social relations rather than to a place or a ...
Charlotta Widmark
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Revisión del contexto ideológico y económico del modelo de focalización
Entramado, 2013 El artículo tiene como propósito mostrar los resultados producto de la revisión del contexto ideológico y económico sobre el cual se desarrolla el modelo de focalización en Colombia. Para ello se realizó el examen de algunas variables económicas así como
Patricia Home-Arias
doaj
Land Readjustment for urban informal settlement upgrading
African Journal on Land Policy and Geospatial SciencesContext and background Land readjustment can be an effective tool for addressing informal settlements arising from rapid urbanisation in Africa. It is a century-old technique that is gaining application as a self-financing mechanism in the context of ...
Patience Mazanhi, Charles, Robert Home
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Of Women, Wine and Salt: Revisioning the Home in Harriet Prescott Spofford’s Detective Fiction
European Journal of American Studies, 2019 Although Harriet Prescott Spofford appears to have given up the genre of detective fiction in the late 1860s, she actually used it as the foundation for works in which suspense, sudden revelations and unexpected final twists serve her investigation of ...
Stéphanie Durrans
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