Results 41 to 50 of about 264,377 (284)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Towards Comprehensive Home Automation: Leveraging the IoT, Node-RED, and Wireless Sensor Networks for Enhanced Control and Connectivity

Engineering Proceedings
Automation seems widespread today, yet it is not implemented in daily life. However, most home automation systems are expensive, object-dependent, and lacking in crucial features.
Likewin Thomas, Manoj Kumar MV, Shiva Darshan SL, Prashanth BS   +3 more
doaj   +1 more source

Smart Home Automation Using Intelligent Electricity Dispatch

IEEE Access, 2021
The evolution of technology has increased the consumption of electric power locally and globally which lead to a dramatic increase in demand for electric power. Electricity consumption rate in different forms at home and commercially increased. Sometimes,
Muhammad Javed Iqbal, Muhammad Munwar Iqbal, Iftikhar Ahmad, Muneer Ahmad, N. Z. Jhanjhi, Sultan Aljahdali, Memoona Mushtaq   +6 more
doaj   +1 more source

Intelligent Coordination and Automation for Smart Home Accessories [PDF]

, 2017
Smarthome accessories are rapidly becoming more popular. Although many companies are making devices to take advantage of this market, most of the created smart devices are actually unintelligent.
Choulos, Alexander, Zhang, Tian
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Improving Home Automation Security; Integrating Device Fingerprinting Into Smart Home

IEEE Access, 2016
This paper explains the importance of accessing modern smart homes over the Internet, and highlights various security issues associated with it. This paper explains the evolution of device fingerprinting concept over time, and discusses various pitfalls ...
Arun Cyril Jose, Reza Malekian, Ning Ye
doaj   +1 more source

Analysis and comparison of Scalextric, SCX, and Carrera Digital slot car systems: A mechatronic engineering design case study [PDF]

, 2014
Digital slot cars operate by transmitting both power and data over a single pair of wires much like DCC-controlled model railways and some home automation systems.
Bradley, Neil, Gaylard, Carl, Harrison, Matthew, Kim, Mirae, Li, Victor, Nel, Kirsten, Scott, Jonathan B., Seabright, Matthew, Song, Chris, Tritscher, Daniel   +9 more
core   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source