Results 41 to 50 of about 266,738 (289)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A Prosumer-Oriented, Interoperable, Modular and Secure Smart Home Energy Management System Architecture

open access: yesSmart Cities, 2022
As prices on renewable energy electricity generation and storage technologies decrease, previous standard home energy end-users are also becoming producers (prosumers). Together with the increase of Smart Home automation and the need to manage the energy-
Pedro Gonzalez-Gil   +2 more
doaj   +1 more source

An automated and versatile ultra-low temperature SQUID magnetometer [PDF]

open access: yes, 2004
We present the design and construction of a SQUID-based magnetometer for operation down to temperatures T = 10 mK, while retaining the compatibility with the sample holders typically used in commercial SQUID magnetometers.
A. Morello   +8 more
core   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Towards Comprehensive Home Automation: Leveraging the IoT, Node-RED, and Wireless Sensor Networks for Enhanced Control and Connectivity

open access: yesEngineering Proceedings
Automation seems widespread today, yet it is not implemented in daily life. However, most home automation systems are expensive, object-dependent, and lacking in crucial features.
Likewin Thomas   +3 more
doaj   +1 more source

Intelligent Coordination and Automation for Smart Home Accessories [PDF]

open access: yes, 2017
Smarthome accessories are rapidly becoming more popular. Although many companies are making devices to take advantage of this market, most of the created smart devices are actually unintelligent.
Choulos, Alexander, Zhang, Tian
core   +1 more source

Determination of the influence of specific building regulations in smart buildings [PDF]

open access: yes, 2014
The automation of domestic services began to be implemented in buildings since the late nineteenth century, and today we are used to terms like ‘intelligent buildings’, ‘digital home’ or ‘domotic buildings’.
Abdulkadir Ganah   +6 more
core   +2 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Improving Home Automation Security; Integrating Device Fingerprinting Into Smart Home

open access: yesIEEE Access, 2016
This paper explains the importance of accessing modern smart homes over the Internet, and highlights various security issues associated with it. This paper explains the evolution of device fingerprinting concept over time, and discusses various pitfalls ...
Arun Cyril Jose, Reza Malekian, Ning Ye
doaj   +1 more source

Home - About - Disclaimer - Privacy