Results 161 to 170 of about 4,469,958 (240)

Living Low and Dry: Costs of and Resilience to Soil Hydric Stress in a Fossorial Amphisbaenian Reptile

Integrative Zoology, EarlyView.
Soil drought imposes moderate, temporary costs on a strictly fossorial amphisbaenian reptile. However, these animals seem to cope with, at least, moderately short droughts thanks to their peculiar adaptations to living in an underground environment. ABSTRACT The physiological traits of animals can be strongly influenced by climatic fluctuations, and ...
José Martín, Álvaro Navarro‐Castilla, Alejandro de la Concha, José Javier Cuervo, Isabel Barja, Pilar López   +5 more
wiley   +1 more source

Challenges and expectations on the use of automated home cage monitoring for advancing laboratory animal care and welfare. [PDF]

Lab Anim
Tremoleda JL, Brønstad A, Potschka H, Seebeck P, Stiedl O, Voikar V, Wells S, TEATIME Animal Welfare Subgroup.   +7 more
europepmc   +1 more source

Intra‐ and Interspecific Effects on Spatio‐Temporal Behavior of Common Commensal Rodent Species

Integrative Zoology, EarlyView.
This study revealed major findings on spatio‐temporal behavior of commensal rodents on a pig farm showing the influence of interspecific dominance on movement behavior and the resulting species‐specific ecological adaptations. Additionally, rodents tend to stay in their home ranges and migration to other stable buildings is only rare.
Florian Huels, Vincent Sluydts, Dries Vermeiren, Marina Voinson, Lucinda Kirkpatrick, Ivan Herrera Olivares, Herwig Leirs, Jens Jacob, Bram Vanden Broecke   +8 more
wiley   +1 more source

Disentangling Multitrophic Interactions: How Vegetation Cover, Wild Boar, Deer, and Predators Shape Rodents Activity and Acorn Dispersal

Integrative Zoology, EarlyView.
Vegetation cover promotes rodent activity and acorn dispersal, while wild boars exert a direct negative effect on mice. Conversely, deer and predators displayed no significant impact on rodent behavior. These results identify wild boars as the main disruptors of rodent‐mediated forest regeneration.
David Notario Rincón, Alberto Muñoz, Rafael Barrientos, Álvaro Gaytán, Lucía Cano, Pablo Quiles, Luis Sánchez, Alejandro Redondo, Alexander Cisneros, Raúl Bonal   +9 more
wiley   +1 more source

Advocating for automation in animal research: using home cage monitoring to advance welfare, reproducibility and scientific openness. [PDF]

Dis Model Mech
COST Action TEATIME CA20135 welfare group.
europepmc   +1 more source

Tree Squirrels Selectively Disperse High‐Quality Acorns Away From Tree Trunks

Integrative Zoology, EarlyView.
Acorn quality and squirrel feeding behavior significantly structured spatial dispersal patterns of two Californian oak species. Non‐infested acorns were preferentially selected for embryo excision and dispersed farther than infested ones. Acorns were fully consumed near tree trunks, signaling rapid feeding in safe refuges, whereas non‐eaten, partially ...
Miguel Puente‐Ruiz, Raquel Muñoz‐Gallego, Marta Peláez, Rodolfo Dirzo, Ramón Perea   +4 more
wiley   +1 more source

The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment

British Journal of Pharmacology, EarlyView.
Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton, Fraser Nunn, Erika Lace, Álvaro Lorente‐Macías, Rachel Toth, Asier Unciti‐Broceta, Tim G. Hales   +6 more
wiley   +1 more source

Editorial: Home Cage-Based Phenotyping in Rodents: Innovation, Standardization, Reproducibility and Translational Improvement

Frontiers in Neuroscience, 2022
Stefano Gaburro, York Winter, Maarten Loos, Jeansok J. Kim, Oliver Stiedl   +4 more
doaj   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi, Laura Mundrucz, Máté Deák, Angéla Kecskés, Éva Borbély, Viktória Kormos, Balázs Gaszner, Orsolya Mihály, Balázs István Tóth, Joris Vriens, Thomas Voets, Erzsébet Kövesdi, Miklós Kecskés   +12 more
wiley   +1 more source

Bioengineered microbiotic levodopa therapy improves cognition and reduces pathology in a rat model of Alzheimer's disease

British Journal of Pharmacology, EarlyView.
Background and Purpose Degeneration of the pontine noradrenergic and midbrain dopaminergic systems contributes to cognitive‐behavioural disturbances during the prodromal stages of Alzheimer's disease (AD). We developed a genetically engineered, programmable probiotic Escherichia coli Nissle 1917 strain (EcNrhaL‐DOPA) capable of producing L‐3,4 ...
Mona Abdelhamid, Piyush Padhi, Mahsa Gifani, John S. Beck, Jacob P. Thomas, Gargi Khadse, Catherine Kudela, Gregory J. Phillips, Anumantha G. Kanthasamy, Scott E. Counts   +9 more
wiley   +1 more source