Results 41 to 50 of about 4,469,958 (240)

Protocol for non-invasive assessment of spontaneous movements of group-housed animals using remote video monitoring

STAR Protocols, 2022
Summary: Frequent monitoring of laboratory animals is critical for ensuring animal welfare and experimental data collection. To minimize the adverse and confounding effects caused by current monitoring protocols and human presence, we developed a low ...
Alan David Marcus, Satyanarayana Achanta, Sven-Eric Jordt   +2 more
doaj   +1 more source

Non-intrusive high throughput automated data collection from the home cage

Heliyon, 2019
Automated home cage monitoring represents a key technology to collect animal activity information directly from the home cage. The availability of 24/7 cage data enables extensive and quantitative assessment of mouse behavior and activity over long ...
Fabio Iannello
doaj   +1 more source

Effects of Cage Position and Light Transmission on Home Cage Activity and Circadian Entrainment in Mice

Frontiers in Neuroscience, 2022
Light is known to exert powerful effects on behavior and physiology, including upon the amount and distribution of activity across the day/night cycle.
Laura C. E. Steel, Selma Tir, Shu K. E. Tam, James N. Bussell, Manuel Spitschan, Manuel Spitschan, Russell G. Foster, Stuart N. Peirson   +7 more
doaj   +1 more source

Editorial: Home cage-based phenotyping in rodents: innovation, standardization, reproducibility, and translational improvement, volume II [PDF]

Frontiers in Neuroscience
Lars Lewejohann, Lars Lewejohann, Oliver Stiedl, Stefano Gaburro, Stefano Gaburro, Silvia Mandillo   +5 more
doaj   +2 more sources

Creating Detailed Metadata for an R Shiny Analysis of Rodent Behavior Sequence Data Detected Along One Light-Dark Cycle

Frontiers in Neuroscience, 2021
Automated mouse phenotyping through the high-throughput analysis of home cage behavior has brought hope of a more effective and efficient method for testing rodent models of diseases. Advanced video analysis software is able to derive behavioral sequence
Julien Colomb, York Winter, York Winter
doaj   +1 more source

On the Digital Psychopharmacology of Valproic Acid in Mice

Frontiers in Neuroscience, 2020
Antiepileptic drugs (AEDs) require daily ingestion for maximal seizure prophylaxis. Adverse psychiatric consequences of AEDs present as: (i) reversible changes in mood, anxiety, anger and/or irritability that often necessitate drug discontinuation, and ...
John Samuel Bass, Anney H. Tuo, Linh T. Ton, Miranda J. Jankovic, Paarth K. Kapadia, Catharina Schirmer, Vaishnav Krishnan   +6 more
doaj   +1 more source

Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project.

PLoS ONE, 2017
Measuring the activity and temperature of rats is commonly required in biomedical research. Conventional approaches necessitate single housing, which affects their behavior and wellbeing.
William S Redfern, Karen Tse, Claire Grant, Amy Keerie, David J Simpson, John C Pedersen, Victoria Rimmer, Lauren Leslie, Stephanie K Klein, Natasha A Karp, Rowland Sillito, Agis Chartsias, Tim Lukins, James Heward, Catherine Vickers, Kathryn Chapman, J Douglas Armstrong   +16 more
doaj   +1 more source

Home-cage behavior in the Stargazer mutant mouse

Scientific Reports, 2022
In many childhood-onset genetic epilepsies, seizures are accompanied by neurobehavioral impairments and motor disability. In the Stargazer mutant mouse, genetic disruptions of Cacng2 result in absence-like spike-wave seizures, cerebellar gait ataxia and ...
Catharina Schirmer, Mark A. Abboud, Samuel C. Lee, John S. Bass, Arindam G. Mazumder, Jessica L. Kamen, Vaishnav Krishnan   +6 more
doaj   +1 more source

Refinement of IntelliCage protocols for complex cognitive tasks through replacement of drinking restrictions by incentive-disincentive paradigms

Frontiers in Behavioral Neuroscience, 2023
The IntelliCage allows automated testing of cognitive abilities of mice in a social home cage environment without handling by human experimenters. Restricted water access in combination with protocols in which only correct responses give access to water ...
Xueqian Ma, Beatrice Schildknecht, Adrian C. Steiner, Irmgard Amrein, Irmgard Amrein, Martina Nigri, Giulia Bramati, David P. Wolfer, David P. Wolfer   +8 more
doaj   +1 more source

A non-invasive digital biomarker for the detection of rest disturbances in the SOD1G93A mouse model of ALS

, 2021
Webinar on the application of home cage based-phenotyping on models of neurodegenerative diseases within the Research Topic on Home Cage Monitoring hosted by the journal Frontiers in ...
Mandillo Silvia
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