Results 51 to 60 of about 4,469,958 (240)

Towards substitution of invasive telemetry: An integrated home cage concept for unobtrusive monitoring of objective physiological parameters in rodents.

PLoS ONE, 2023
This study presents a novel concept for a smart home cage design, tools, and software used to monitor the physiological parameters of mice and rats in animal-based experiments.
Lucas Mösch, Janosch Kunczik, Lukas Breuer, Dorit Merhof, Peter Gass, Heidrun Potschka, Dietmar Zechner, Brigitte Vollmar, René Tolba, Christine Häger, André Bleich, Michael Czaplik, Carina Barbosa Pereira   +12 more
doaj   +1 more source

Image_3_Automated Home-Cage Monitoring During Acute Experimental Colitis in Mice.TIF

, 2021
For ethical and legal reasons it is necessary to assess the severity of procedures in animal experimentation. To estimate the degree of pain, suffering, distress or lasting harm, objective methods that provide gradebale parameters need to be tested and ...
André Bleich (2201215), Eva Zentrich (11595058), Steven R. Talbot (9569190), Christine Häger (833964)   +3 more
core   +1 more source

Automated home-cage for the evaluation of innate non-reflexive pain behaviors in a mouse model of inflammatory pain

Scientific Reports, 2021
The failure to develop analgesic drugs is attributed not only to the complex and diverse pathophysiology of pain in humans but also to the poor experimental design and poor preclinical assessment of pain.
Hasriadi, Peththa Wadu Dasuni Wasana, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat   +4 more
doaj   +1 more source

Image_1_Automated Home-Cage Monitoring During Acute Experimental Colitis in Mice.TIF

, 2021
For ethical and legal reasons it is necessary to assess the severity of procedures in animal experimentation. To estimate the degree of pain, suffering, distress or lasting harm, objective methods that provide gradebale parameters need to be tested and ...
André Bleich (2201215), Eva Zentrich (11595058), Steven R. Talbot (9569190), Christine Häger (833964)   +3 more
core   +1 more source

Image_2_Automated Home-Cage Monitoring During Acute Experimental Colitis in Mice.TIF

, 2021
For ethical and legal reasons it is necessary to assess the severity of procedures in animal experimentation. To estimate the degree of pain, suffering, distress or lasting harm, objective methods that provide gradebale parameters need to be tested and ...
André Bleich (2201215), Eva Zentrich (11595058), Steven R. Talbot (9569190), Christine Häger (833964)   +3 more
core   +1 more source

Table_1_Automated Home-Cage Monitoring During Acute Experimental Colitis in Mice.docx

, 2021
For ethical and legal reasons it is necessary to assess the severity of procedures in animal experimentation. To estimate the degree of pain, suffering, distress or lasting harm, objective methods that provide gradebale parameters need to be tested and ...
André Bleich (2201215), Eva Zentrich (11595058), Steven R. Talbot (9569190), Christine Häger (833964)   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Towards large scale automated cage monitoring - Diurnal rhythm and impact of interventions on in-cage activity of C57BL/6J mice recorded 24/7 with a non-disrupting capacitive-based technique.

PLoS ONE, 2019
BACKGROUND AND AIMS:Automated recording of laboratory animal's home cage behavior is receiving increasing attention since such non-intruding surveillance will aid in the unbiased understanding of animal cage behavior potentially improving animal ...
Karin Pernold, F Iannello, B E Low, M Rigamonti, G Rosati, F Scavizzi, J Wang, M Raspa, M V Wiles, B Ulfhake   +9 more
doaj   +1 more source

Open-Source, Low Cost, Free-Behavior Monitoring, and Reward System for Neuroscience Research in Non-human Primates

Frontiers in Neuroscience, 2017
We describe a low-cost system designed to document bodily movement and neural activity and deliver rewards to monkeys behaving freely in their home cage.
Tyler Libey, Eberhard E. Fetz, Eberhard E. Fetz, Eberhard E. Fetz   +3 more
doaj   +1 more source

Image_4_Automated Home-Cage Monitoring During Acute Experimental Colitis in Mice.TIF

, 2021
For ethical and legal reasons it is necessary to assess the severity of procedures in animal experimentation. To estimate the degree of pain, suffering, distress or lasting harm, objective methods that provide gradebale parameters need to be tested and ...
André Bleich (2201215), Eva Zentrich (11595058), Steven R. Talbot (9569190), Christine Häger (833964)   +3 more
core   +1 more source