Results 31 to 40 of about 4,469,958 (240)

Continuous Home Cage Monitoring of Activity and Sleep in Mice During Repeated Paroxetine Treatment and Discontinuation [PDF]

Psychopharmacology, 2023
Raquel Pinacho, Trevor Sharp, David M Bannerman   +2 more
exaly   +2 more sources

Development and application of home cage monitoring in laboratory mice and rats: a systematic review

, 2022
We are conducting a systematic review on home cage monitoring in laboratory mice and rats. A major advantage of home cage monitoring is that the animals can be examined in their home environment, which reduces stress and allows to monitor the animals 24 ...
Marion Rivalan, Sabine Hölter, Petra Seebeck, Anne Habedank, Oliver Stiedl, Brun Ulfhake, Silvia Mandillo, Julijana Trifkovic, Lars Lewejohann, Paul Mieske, Pia Kahnau, Nicolas Torquet, Hamid Meziane, Sylvia Badurek, Srećko Gajovć, Giuseppe Di Giovanni, Vootele Voikar, Aleksandra Bartelik, Dragan Hrncic, Jenny Wilzopolski, Adriana Amfim, Nuno Henrique Franco, Katharina Hohlbaum, Benjamin Lang, Anna Kiryk, Aurelija Radzevičienė, Elisabetta Golini, Yann Hérault, Natasa Loncarevic-Vasiljkovic, Elodie Ey, Otto Kalliokoski, Kai Diederich, Maša Čater, Angela Caruso, Jan Rozman, Christa Thöne-Reineke, Maria Luisa Scattoni   +36 more
core   +5 more sources

Long-Term Effects of Low-Intensity Blast Non-Inertial Brain Injury on Anxiety-Like Behaviors in Mice: Home-Cage Monitoring Assessments [PDF]

Neurotrauma Reports, 2022
Zezong Gu, Jiankun Cui, Shanyan Chen
exaly   +2 more sources

The potential of home cage monitoring to screen mice for sleep disturbances

, 2021
Sleep disturbances are common in the general population and even more common as symptoms and comorbidities in many neurological and neuropsychiatric disorders like Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Myotonic Dystrophies, Autism, Schizophrenia, Bipolar Disorder, Major Depression.
Silvia Mandillo
openaire   +2 more sources

SMART CAGES, BETTER WELFARE: SUPPORTING THE 3RS IN ANIMAL RESEARCH WITH HOME-CAGE MONITORING AND SYSTEM SELECTION

Slovenian Veterinary Research
High welfare standards for animals used in research is as much an ethical issue as it is a cornerstone of high-quality science. Researchers can improve both animal welfare and data reliability by implementing strategies that reduce stress in ...
Rohish Kaura, Dragan Hrnčić, Amela Dervišević, Veronika Borbelyova, Ozge Selin Cevik, Marija Heffer, Maša Čater   +6 more
doaj   +2 more sources

Monitoring Group Activity of Hamsters and Mice as a Novel Tool to Evaluate COVID-19 Progression, Convalescence, and rVSV-ΔG-Spike Vaccination Efficacy

Frontiers in Bioengineering and Biotechnology, 2021
The COVID-19 pandemic initiated a worldwide race toward the development of treatments and vaccines. Small animal models included the Syrian golden hamster and the K18-hACE2 mice infected with SARS-CoV-2 to display a disease state with some aspects of ...
Sharon Melamed, Boaz Politi, Ettie Grauer, Hagit Achdout, Moshe Aftalion, David Gur, Hadas Tamir, Yfat Yahalom-Ronen, Shlomy Maimon, Efi Yitzhak, Shay Weiss, Amir Rosner, Noam Erez, Shmuel Yitzhaki, Shmuel C Shapira, Nir Paran, Emanuelle Mamroud, Yaron Vagima, Tomer Israely   +18 more
doaj   +1 more source

Data repurposing from digital home cage monitoring enlightens new perspectives on mouse motor behaviour and reduction principle. [PDF]

Sci Rep, 2023
In this longitudinal study we compare between and within-strain variation in the home-cage spatial preference of three widely used and commercially available mice strains—C57BL/6NCrl, BALB/cAnNCrl and CRL:CD1(ICR)—starting from the first hour post cage ...
Fuochi S, Rigamonti M, Raspa M, Scavizzi F, de Girolamo P, D'Angelo L.   +5 more
europepmc   +3 more sources

Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives

Frontiers in Behavioral Neuroscience, 2021
The reproducibility crisis (or replication crisis) in biomedical research is a particularly existential and under-addressed issue in the field of behavioral neuroscience, where, in spite of efforts to standardize testing and assay protocols, several ...
Fabrizio Grieco, Briana J. Bernstein, Barbara Biemans, Lior Bikovski, Lior Bikovski, C. Joseph Burnett, Jesse D. Cushman, Elsbeth A. van Dam, Sydney A. Fry, Bar Richmond-Hacham, Judith R. Homberg, Martien J. H. Kas, Helmut W. Kessels, Bastijn Koopmans, Michael J. Krashes, Vaishnav Krishnan, Sreemathi Logan, Maarten Loos, Katharine E. McCann, Qendresa Parduzi, Chaim G. Pick, Chaim G. Pick, Chaim G. Pick, Thomas D. Prevot, Gernot Riedel, Lianne Robinson, Mina Sadighi, August B. Smit, William Sonntag, Reinko F. Roelofs, Ruud A.J. Tegelenbosch, Lucas P.J.J. Noldus, Lucas P.J.J. Noldus   +32 more
doaj   +1 more source

On the importance of including both sexes in animal studies - insights from home-cage monitoring. [PDF]

Biol Rev Camb Philos Soc
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Čater M, Dušek A, Bartelik A, Mandillo S, Golini E, Rigamonti M, Bains RS, Forrest H, Rivalan M, Long M, Kiryk A, Lewejohann L, Franco NH.   +12 more
europepmc   +4 more sources

Mineralocorticoid receptor deletion alters spontaneous behavior in an automated home-cage monitoring apparatus. [PDF]

Horm Behav
Mineralocorticoid receptors (MRs) are transcription factors expressed throughout the body and brain, with especially high expression in the hippocampal area CA2. MRs are essential for maintaining the physiological stress response and regulating the hypothalamic-pituitary adrenal (HPA) axis.
Kendricks DR, Sleiman SJ, Fry SA, Stallone J, Bernstein BJ, Stevanovic KD, Aksu LR, Alexander GM, McCann KE, Dudek SM, Cushman JD.   +10 more
europepmc   +4 more sources