Low-cost solution for rodent home-cage behaviour monitoring.
PLoS ONE, 2019 In the current research on measuring complex behaviours/phenotyping in rodents, most of the experimental design requires the experimenter to remove the animal from its home-cage environment and place it in an unfamiliar apparatus (novel environment ...
Surjeet Singh +4 more
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MouseVUER: video based open-source system for laboratory mouse home-cage monitoring [PDF]
Scientific ReportsVideo monitoring of mice in the home-cage reveals behavior profiles without the disruptions caused by specialized test setups and makes it possible to quantify changes in behavior patterns continually over long time frames.
Ghadi Salem +12 more
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Correction: Low-cost solution for rodent home-cage behaviour monitoring.
PLoS ONE, 2019 [This corrects the article DOI: 10.1371/journal.pone.0220751.].
PLOS ONE Staff
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The SnackerTracker: A novel home-cage monitoring device for measuring food-intake and food-seeking behaviour in mice [version 2; peer review: 2 approved] [PDF]
Wellcome Open ResearchBackground Accurately measuring activity and feeding is important in laboratory animal research, whether for welfare-monitoring or experimental recording.
Vladyslav Vyazovskiy +8 more
doaj +4 more sources
From observation to optimization: behavioral metrics that matter in KPI based home cage monitoring [PDF]
Frontiers in Behavioral NeuroscienceMost in vivo scientists would agree that digital biomarkers collected via home-cage monitoring generate valuable data. However, few can tell precisely how valuable.
Steven R. Talbot +4 more
doaj +5 more sources
Focus on novel approaches: Home-cage monitoring of laboratory mice [PDF]
, 2023 Assessment of behavioural phenotype is crucial for the evaluation of various disease models, particularly in laboratory rodents. Traditionally, this includes performing a variety of conventional tests where animals are removed from their home-cages and placed in behavioural test apparatuses.
Aleksandra Bartelik +4 more
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Beyond Single Metrics: Multi-Parameter Home-Cage Monitoring Improves Welfare Assessment. [PDF]
Laboratory AnimalsSingle outcome measures often fall short of the sensitivity and objectivity expected under European Directive 2010/63, particularly in fast progressing disease models. To address this gap, the German Research Foundation consortium FOR2591 collated data from 55 routinely used models in six species and narrowed more than 50 candidate readouts down to a ...
René Tolba +2 more
exaly +4 more sources
Longitudinal home-cage automated assessment of climbing behavior shows sexual dimorphism and aging-related decrease in C57BL/6J healthy mice and allows early detection of motor impairment in the N171-82Q mouse model of Huntington’s disease [PDF]
Frontiers in Behavioral Neuroscience, 2023 Monitoring the activity of mice within their home cage is proving to be a powerful tool for revealing subtle and early-onset phenotypes in mouse models. Video-tracking, in particular, lends itself to automated machine-learning technologies that have the ...
Rasneer S. Bains +7 more
doaj +2 more sources
Dual-Stream Spatiotemporal Networks with Feature Sharing for Monitoring Animals in the Home Cage
Sensors, 2023 This paper presents a spatiotemporal deep learning approach for mouse behavioral classification in the home-cage. Using a series of dual-stream architectures with assorted modifications for optimal performance, we introduce a novel feature sharing ...
Ezechukwu Israel Nwokedi +5 more
doaj +6 more sources
Refining drug screening with automated home cage monitoring: a crossover study in socially housed rats [PDF]
Frontiers in ToxicologyAttrition in drug development due to central nervous system (CNS)-related adverse events is costly and can pose risks to volunteer safety during clinical development, underscoring the need to refine preclinical CNS screening strategies.
David A. Connor +5 more
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