Results 61 to 70 of about 837,191 (303)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

The effect of paracetamol on care dependency and daily functioning in persons with advanced dementia living in long-term care facilities

open access: yesBMC Geriatrics
Background Pain medication may have an impact on the quality of life (QoL) in persons with dementia, but may also influence care dependency and daily functioning.
Paulien H van Dam   +3 more
doaj   +1 more source

Assessment of a self-reported Drinks Diary for the estimation of drinks intake by care home residents: Fluid Intake Study in the Elderly (FISE) [PDF]

open access: yes, 2015
Objectives: We evaluated the accuracy of a newly developed self-completed Drinks Diary in care home residents and compared it with direct observation and fluid intake charts. Design: Observational study.
ASS Shapiro   +24 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

FACTORS ANALYZE ABOUT WILLINGNESS OF ELDERLY TO STAY IN ELDERLY FOLK HOME

open access: yesJurnal Ners, 2017
Introduction : Moving to the new house is not easy for the elderly, especially moving to the elderly folk home. A lot of elderly refuse to stay in the elderly folk home. Some conditions which make the elderly give their willingness to stay in the elderly
I Ketut Sudiana   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

kurz und kn@pp news : Nr. 15 [engl. Fassung] [PDF]

open access: yes, 2009
* International Study on Medical Homes * Learning from mistakes * Optimizing medication for elderly, multimorbid patients * The Safety culture in German family practices * 2nd Frankfurt General Practice Day: Now online* Internationale

core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Serviços de atenção ao idoso e estratégias de cuidado domiciliares e institucionais

open access: yesRevista Brasileira de Geriatria e Gerontologia
INTRODUÇÃO: As redes de atenção à saúde são fundamentais para assistir a população idosa em seus diversos aspectos. A assistência domiciliar, o Programa Acompanhante de Idosos da Secretaria Municipal da Saúde da cidade de São Paulo e as instituições de ...
Fernanda Pretti Chalet Ferreira   +2 more
doaj   +1 more source

Perbedaan Tingkat Depresi Antara Lansia Yang Tinggal Di Pstw Dengan Lansia Yang Tinggal Di Tengah Keluarga [PDF]

open access: yes, 2016
Depression is the most often psychiatric disorder occurs in elderly. Residence difference was reposted as predictor of depression in elderly. This study aimed to compare the depression scale between elderly people who lived in nursing home and elderly ...
', A. (Arneliwati)   +2 more
core  

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