Results 71 to 80 of about 3,024,874 (379)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells

Cell & Bioscience, 2023
Background Spermatogenesis depends on the supporting of the Sertoli cells and their communications with germ cells. However, the regulation of crosstalk between the Sertoli cells and germ cells remains unclear. Results In this report, we used conditional
Fengling Lai, Haoyu Wang, Xinyue Zhao, Kangning Yang, Le Cai, Mengxin Hu, Lan Lin, Xizhong Xia, Wei Li, Hanhua Cheng, Rongjia Zhou   +10 more
doaj   +1 more source

Acinetobacter tandoii ZM06 Assists Glutamicibacter nicotianae ZM05 in Resisting Cadmium Pressure to Preserve Dipropyl Phthalate Biodegradation

Microorganisms, 2021
Dipropyl phthalate (DPrP) coexists with cadmium as cocontaminants in environmental media. A coculture system including the DPrP-degrading bacterium Glutamicibacter nicotianae ZM05 and the nondegrading bacterium Acinetobacter tandoii ZM06 was artificially
Xuejun Wang, Si Shen, Hao Wu, Haixia Wang, Lvjing Wang, Zhenmei Lu   +5 more
doaj   +1 more source

Correction: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis [PDF]

, 2022
Debangshu Samanta, Youngrok Park, Shaida A. Andrabi, Laura M. Shelton, Daniele M. Gilkes, Gregg L. Semenza   +5 more
openalex   +1 more source

Homeostasis Patterns

SIAM Journal on Applied Dynamical Systems
36 pages, 10 figures, 2 ...
William Duncan, Fernando Antoneli, Janet Best, Martin Golubitsky, Jiaxin Jin, H. Frederik Nijhout, Mike Reed, Ian Stewart   +7 more
openaire   +3 more sources

Tryptophan Metabolism and Gut-Brain Homeostasis

International Journal of Molecular Sciences, 2021
Tryptophan is an essential amino acid critical for protein synthesis in humans that has emerged as a key player in the microbiota-gut-brain axis. It is the only precursor for the neurotransmitter serotonin, which is vital for the processing of emotional ...
W. Roth, Kimia Zadeh, Rushi Vekariya, Yong Ge, M. Mohamadzadeh   +4 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Mitochondrial DNA: Distribution, Mutations, and Elimination

Cells, 2019
Mitochondrion harbors its own DNA (mtDNA), which encodes many critical proteins for the assembly and activity of mitochondrial respiratory complexes. mtDNA is packed by many proteins to form a nucleoid that uniformly distributes within the mitochondrial ...
Chaojun Yan, Xiaoying Duanmu, Ling Zeng, Bing Liu, Zhiyin Song   +4 more
doaj   +1 more source

A Small Cysteine-Free Protein Acts as a Novel Regulator of Fungal Insect-Pathogenic Lifecycle and Genomic Expression

mSystems, 2021
Small secreted proteins (SSPs), particularly cysteine-rich proteins secreted during fungal infection, comprise virulence effectors in plant-pathogenic fungi but remain unknown in insect-pathogenic fungi.
Ya-Ni Mou, Bo Fu, Kang Ren, Sheng-Hua Ying, Ming-Guang Feng   +4 more
doaj   +1 more source

Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. [PDF]

, 2015
Background & aimsAll-trans Retinoic acid (RA) regulates hepatic lipid and bile acid homeostasis. Similar to bile acid (BA), RA accelerates partial hepatectomy (PHx)-induced liver regeneration.
Hu, Ying, Liu, Hui-Xin, Wan, Yu-Jui Yvonne   +2 more
core   +2 more sources