Results 81 to 90 of about 2,139,288 (317)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station

npj Microgravity
The analysis of cells frozen within the International Space Station (ISS) will provide crucial insights into the impact of the space environment on cellular functions and properties.
Hiroto Ishii, Rin Endo, Sanae Hamanaka, Nobuyuki Hidaka, Maki Miyauchi, Naho Hagiwara, Takahisa Miyao, Tohru Yamamori, Tatsuya Aiba, Nobuko Akiyama, Taishin Akiyama   +10 more
doaj   +1 more source

Homeostasis

, 2011
Introduction to the principles of homeostasis.

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genome streamlining of Pseudomonas putida B6-2 for bioremediation

mSystems
Microbial transformation is a favored approach for environmental remediation. However, the effectiveness of microbial remediation has been limited by the lack of chassis cells with satisfactory contaminant degradation performance. Pseudomonas putida B6-2,
Siqing Fan, Hao Ren, Xueni Fu, Xiangyu Kong, Hao Wu, Zhenmei Lu   +5 more
doaj   +1 more source

Interpersonal homeostasis and network homeostasis [PDF]

Various phenomena have recently been studied using network theory. It has been reported that homeostasis on networks can be classified with a mathematical definition. The classification relates to the network’s topology.
竹内幸子
core  

Targeting Mitochondrial Homeostasis: The Role of Acupuncture in Depression Treatment

, 2023
Haiyang Chen,1,* Chenlin Wu,2,* Qin Lv,2 Mingjie Li,1 Lu Ren2,3 1Department of Acupuncture and Moxibustion, Liaoning University of Traditional Chinese Medicine, Shenyang, 110847, People’s Republic of China; 2Graduate School, Liaoning University ...
Ren L, Wu C, Chen H, Li M, Lv Q
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Combined computational, rational, and empirical design of boiling-resistant keratinase

Applied and Environmental Microbiology
Engineering of highly thermostable keratinase is of great theoretical interest in understanding protein stability mechanisms and practical significance for processing keratinous wastes such as feathers and wool.
Yong Yang, Yuewen Luo, Yidi Ding, Yitong Yao, Jie Liu, Zinan Xu, Yu Li, Huai Li, Fei Gan, Xiao-Feng Tang, Bing Tang   +10 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source