Results 51 to 60 of about 609,666 (313)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Emotional Experiences of Elderly People Regarding the Process of Residency in Nursing Homes

نشریه پرستاری ایران, 2007
Background & Aim: There isincreasing rate of tendency of leaving elderly people to live in nursing homes in recent years. It is suggested that, the common view of the elderly people towards living in nursing homes is known as "the final sign of failure ...
Sh. Salarvand, H. Abedi, H. Hosseini, Sh. Salehi, M. Keyvanara   +4 more
doaj  

Drug wastage among the elderly living in old aged homes in Hong Kong [PDF]

, 2013
The extend of drug wastage among elderly living in old aged homes was never investigated. Upon the completion of the previous study on pharmaceutical services provided to elderly living in old aged homes, the amount of drugs wasted from 3,020 residents ...
Chan, EW, Chan, PWL, Cheng, M, Wong, AYS, Wong, ICK   +4 more
core  

Variation in ambulance call rates for care homes in Torbay, UK [PDF]

, 2016
Emergency ambulance calls represent one of the routes of emergency hospital admissions from care homes. We aimed to describe the pattern of ambulance call rates from care homes and identify factors predicting those homes calling for an ambulance most ...
Dickens, C, Hancock, J, Lang, I, Matthews, JN, Somerfield, D, Ukoumunne, OC, Wenman, J   +6 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Economic integration and mature portfolios [PDF]

, 2008
This paper documents and studies sources of international differences in participation and holdings in stocks, private businesses, and homes among households aged 50+ in the US, England, and eleven continental European countries, using new ...
Christelis, Dimitris, Georgarakos, Dimitris, Haliassos, Michael   +2 more
core  

Older care-home residents as collaborators or advisors in research: a systematic review [PDF]

, 2016
Background: patient and public involvement (PPI) in research can enhance its relevance. Older care-home residents are often not involved in research processes even when studies are care-home focused.
Andrea Kenkmann, Anne Killett, Bridget Penhale, Dewar, Fiona Poland, Froggatt, Gordon, Hewitt, Kathleen Lane, Killett, Tamara Backhouse   +10 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

General Self-Efficacy and Associated Factors among Elderly Residents of Nursing Home

Journal of Holistic Nursing and Midwifery, 2016
Introduction:Elderly people encounter with multiple disabilities, stress, anxiety and challenges, which effect on their quality of life. Self-efficacy may encourage them to improve self-care activities, challenges, life satisfaction and quality of their ...
Ladan Naseh, RahimAli Shaikhy, Hossein Rafiei   +2 more
doaj  

Meaning of well-being of older institutionalized persons in abandonment situation [PDF]

Revista Brasileira de Enfermagem
Objective: To understand the meaning of well-being of older persons in situation of abandonment. Methods: a qualitative phenomenological study, carried out in a nursing home in Tepic, Nayarit, from 2017 to 2019.
Wendy Sindy Nallely Flores Martínez, María de Jesús Jiménez González, Norma Elvira Moreno Pérez, Raúl Fernando Guerrero-Castañeda   +3 more
doaj   +4 more sources