Results 131 to 140 of about 10,354 (237)

Directed motivational currents as a framework for mutual-benefit peer teaching in foreign language education. [PDF]

Front Psychol
Ma S.
europepmc   +1 more source

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

The role of parent and teacher involvement in shaping academic emotions. [PDF]

BMC Psychol
Avcı S, Avcu A, Akıncı T, Kafadar EN, Kopuz M, Işkin BE.   +5 more
europepmc   +1 more source

m5C‐Modified tRF3b‐CysGCA‐23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

Advanced Science, EarlyView.
In this study, we identified an NSUN6‐dependent m5C‐modified tsRNA, m5C‐tRF3b CysGCA‐23 (mtRC), that is downregulated in BC and inversely correlated with disease progression. Mechanistically, mtRC suppresses BC malignancy by stabilizing RBM4, attenuating glycolysis, and thereby limiting H3K18 lactylation–mediated activation of IL1RAP and VASH2 ...
Xiaoling Ying, Yapeng Huang, Jian Huang, Qinyu Cai, Danni Zhang, Cong Chen, Yuxi Nie, Baotong Yang, Chuan Li, Wenyu Hu, Chang Xiong, Chengcheng Zhang, Ding Ji, Yaomin Liang, Mei Yang, Wenqi Wu, Weidong Ji   +16 more
wiley   +1 more source

Adaptive actions as a mechanism of change in transdiagnostic internet-delivered cognitive behavioral therapy: Comparison with homework engagement. [PDF]

Internet Interv
Hadjistavropoulos HD, Dear BF, Titov N, Sapkota RP.   +3 more
europepmc   +1 more source

KMT2C Loss Promotes NF2‐Wildtype Meningioma Progression and Ferroptosis Sensitivity via Epigenetic Repression of Hippo Signaling

Advanced Science, EarlyView.
In NF2–wild‐type meningiomas, loss of the epigenetic regulator KMT2C suppresses NF2 transcription and inactivates Hippo signaling, driving tumor progression and increasing ferroptosis sensitivity. Restoration of histone acetylation reverses these effects and inhibits tumor growth, identifying KMT2C as a key regulator linking epigenetic control, NF2 ...
Liuchao Zhang, Yangfan Ye, Wei Gu, Xinyue Wang, Nuo Chen, Qixin He, Lei Xu, Pengzhan Zhao, Guoqiang Fu, Guangyao Yuan, Wenqian Shi, Honglu Chao, Yiming Tu, Jing Ji   +13 more
wiley   +1 more source

The Role of Parenting Styles in Schoolchildren's Homework Motivation, Homework Behavior, and Academic Achievement. [PDF]

Psychol Russ
Gordeeva TO, Nechaeva DM, Sychev OA.
europepmc   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Cognitive-Behavioral Treatment for Breathlessness in Lung Cancer: A Randomized Controlled Trial. [PDF]

Ann Am Thorac Soc
Lo SB, Arrato NA, Presley CJ, McGinty HL, Otto MW, Andersen BL.   +5 more
europepmc   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source