Results 211 to 220 of about 115,476 (249)

Pro-inflammatory intestinal Th17-cells are tissue-resident, accumulate in the epithelia in Crohn's disease, and predict unresponsiveness to vedolizumab. [PDF]

J Crohns Colitis
Paroni M, Faggiano C, Righetti C, Dusetti I, Ranzani V, Moschetti G, Noviello D, Vasco C, Vecchi M, Landini P, Facciotti F, Abrignani S, Caprioli F, Geginat J.   +13 more
europepmc   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao, Yu He, Wenhao Li, Bo Gong, Han Lin, Jianlin Shi, Yuan Yong, Wencheng Wu   +7 more
wiley   +1 more source

Author Correction: ATF7IP/SETDB1-mediated epigenetic programming regulates thymic homing and T lymphopoiesis of hematopoietic progenitors during embryogenesis. [PDF]

Nat Commun
Chen W, Wu J, She P, Li J, Lan Y, Hu X, Huangfu Y, Wu C, Jin D, Xie P, Zhuang G, Wu Y, Zhang Y, Zon LI, Zhu P, Zhong TP.   +15 more
europepmc   +1 more source

Radiation Resilient Synthetic Antiferromagnets‐Based Neuromorphic Device for Sea Surface Temperature Reconstruction

Advanced Science, EarlyView.
By leveraging strong antiferromagnetic coupling, radiation‐tolerant synthetic antiferromagnetic synaptic devices are developed. Their intrinsic nonlinearity emulates neuronal activation, while linear and symmetric conductance modulation mimics synaptic plasticity.
Mingxu Song, Jiahao Liu, Ruisheng Hu, Teng Xu, Aihua Tang, Zhihong Zhu   +5 more
wiley   +1 more source

Human amniotic membrane as an extracellular matrix scaffold in regenerative endodontics: A cell homing perspective. [PDF]

J Conserv Dent Endod
Ferrao TMC, Ataide IN, Lambor R.
europepmc   +1 more source

A Printed Hydrogel Hybrid Electronic System With Thermoresponsive Adhesion for Neurophysiological Monitoring

Advanced Science, EarlyView.
This work develops a soft hybrid electronic system with printed thermoresponsive hydrogel electrodes, which enables high‐fidelity neural signal acquisition and stimulation. The system precisely assesses median and ulnar nerve injuries in clinical cases, realizing accurate diagnosis of neural impairment while ensuring customized adhesion regulation ...
Bo Pang, Ganguang Yang, Jiacheng Wen, Hangyu Gong, Caixin Gong, Yuqi Qiu, Zhixin Wang, Qingyang Zheng, Sen Zhou, Tianzhao Bu, Jia Tian, Zhouping Yin, Yutian Liu, Hao Wu   +13 more
wiley   +1 more source

Advancing mesenchymal stem cell therapy for kidney diseases in companion animals: from mechanisms to clinical application. [PDF]

Front Vet Sci
Yu Y, Wang Y, Mu Y, Wang S, Zhang X, Song Y.   +5 more
europepmc   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Role of chemokines and their receptors in lesional CD8⁺ T cell homing in Indian Post-Kala-Azar Dermal Leishmaniasis. [PDF]

PLoS Negl Trop Dis
Saha S, Goswami D, Saha M, Chakraborty B, Saha S, Karuri S, Roy M, Chaudhuri SJ, Das NK, Chatterjee U, Chatterjee R, Chatterjee M.   +11 more
europepmc   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source