Results 11 to 20 of about 977,991 (352)

Multiple Roles for Chemokines in Neutrophil Biology

open access: yesFrontiers in Immunology, 2020
Chemokines are recognized as the most critical mediators for selective neutrophil recruitment during inflammatory conditions. Furthermore, they are considered fundamental regulators of neutrophil mobilization from the bone marrow (BM) to the bloodstream ...
Arianna Capucetti   +4 more
doaj   +2 more sources

New Druggable Targets for Rheumatoid Arthritis Based on Insights From Synovial Biology

open access: yesFrontiers in Immunology, 2022
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease characterized by chronic inflammation and destruction of multiple small joints which may lead to systemic complications.
Gurvisha Sandhu, B. K. Thelma
doaj   +2 more sources

Homing and Engraftment of Hematopoietic Stem Cells Following Transplantation: A Pre-Clinical Perspective

open access: yesCurrent Oncology
Hematopoietic stem-cell (HSC) transplantation (HSCT) is used to treat various hematologic disorders. Use of genetically modified mouse models of hematopoietic cell transplantation has been critical in our fundamental understanding of HSC biology and in ...
Tanvir Hasan   +5 more
doaj   +2 more sources

Exploring potential of exosomes drug delivery system in the treatment of cancer: Advances and prospective

open access: yesMedicine in Drug Discovery, 2023
Exosomes are vital for cellular communication and the transfer of materials between cells. Recently, it has been shown that nanoparticles may be used as diagnostic indicators and as a potential medicine delivery strategy due to their nanoscale size and ...
Deepika Yadav, Rishabha Malviya
doaj   +1 more source

Homing in on genomic instability as a therapeutic target in cancer

open access: yesNature Communications, 2021
While genomic instability is a hallmark of cancer, its genetic vulnerabilities remain poorly understood. Identifying strategies that exploit genomic instability to selectively target cancer cells is a central challenge in cancer biology with major ...
C. Bielski, B. Taylor
semanticscholar   +1 more source

Mesenchymal Stromal Cell Homing: Mechanisms and Strategies for Improvement

open access: yesiScience, 2019
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic potential in regenerative medicine, owing to their ability to home damaged tissue and serve as a reservoir of growth factors and regenerative molecules.
Mujib Ullah   +2 more
doaj   +1 more source

Modification of Bacteriophages to Increase Their Association with Lung Epithelium Cells In Vitro

open access: yesPharmaceuticals, 2021
There is currently a renaissance in research on bacteriophages as alternatives to antibiotics. Phage specificity to their bacterial host, in addition to a plethora of other advantages, makes them ideal candidates for a broad range of applications ...
Aurelija M. Grigonyte   +3 more
doaj   +1 more source

Large Scale Homing in Honeybees [PDF]

open access: yes, 2015
Honeybee foragers frequently fly several kilometres to and from vital resources, and communicate those locations to their nest mates by a symbolic dance language.
Pahl, Mario   +3 more
core   +1 more source

Mobile DNA elements in T4 and related phages

open access: yesVirology Journal, 2010
Mobile genetic elements are common inhabitants of virtually every genome where they can exert profound influences on genome structure and function in addition to promoting their own spread within and between genomes.
Belfort Marlene   +2 more
doaj   +1 more source

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