Results 91 to 100 of about 703,597 (255)

Survival of Homo Sapiens –A Retrospect Analysis

open access: yes, 2020
Our understanding of human evolution is in the form of evidence of available fossil remains based on discoveries made in the last two hundred years Most of these discoveries are incidental in nature and they do not have the correct serialization and ...
Reya Santra, Harashawaradhana
core  

Evaluación teórica de las propiedades electrónicas y estructurales que afectan a la conductividad eléctrica en copolímeros de furano-tiofeno

open access: yesRevista Colombiana de Química, 2019
Desde el punto de vista científico y tecnológico ha habido un gran interés en el uso de monosustituyentes de furano y tiofeno como polímeros conductores, debido a sus múltiples aplicaciones como OLED, amplificadores ópticos, nanotecnología, entre otros ...
Jorge Luis Anaya Gil   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Microtomographic Archive of Hominin Fossils from the Swartkrans Formation, South Africa (1948-1967)

open access: yesPaleoAnthropology
Since initial excavations in 1948, the site of Swartkrans, located in the ‘Cradle of Humankind,’ South Africa has yielded hundreds of fossil hominin specimens belonging to species of Paranthropus, Homo, and possibly Australopithecus.
Matthew Skinner   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A matter of evolutionary life and death: an ecological model of growth and development in Homo erectus

open access: yes, 2005
This thesis investigates the evolutionary ecology of Homo erectus, focussing on the differential impact of the environment on the species' life history strategy.
Buckley, Carina A.
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Zur Aktualitaet von Adam Smith Homo oeconomicus und ganzheitliches Menschenbild

open access: yes, 1998
'Adam Smith gilt zwar zu Recht als der Begruender der modernen Volkswirtschaftslehre, aber die anthropologische Fundierung seines Vorgehens steht, wie ausfuehrlich gezeigt wird, im Gegensatz zu dem Versuch heutiger Oekonomen, aus dem Menschenbild der ...
Hottinger, Olaf   +3 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

La Chimère de la Villa Albani

open access: yes, 1898
Homo Léon. La Chimère de la Villa Albani. In: Mélanges d'archéologie et d'histoire, tome 18, 1898. pp.
Homo, Léon
core   +1 more source

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