Results 111 to 120 of about 1,477,310 (345)

Homo patient – Homo creativus

Kwartalnik Filmowy, 2004
Autorka analizuje dramat ludzi starych, chorych, niepotrzebnych, nie tylko jako temat filmowy ale także jako wyznacznik współczesnej kultury. Z jednej strony dokumenty w przejmujący sposób ukazujących wegetację ludzi „czwartego wieku” (Taboo. Memento Mori, reż.
openaire   +2 more sources

Homo et Societas

, 2020

openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Evidence of lead poisoning and the co-occurrence of metabolic disease in Archaic/Early Classical (6th–5th century BCE) Laurion, Greece

Homo
Lead is one of the most toxic heavy metals and environmental pollutants on earth capable of adversely affecting every organ in the human body, with harmful short- and long-term effects. In the Laurion region of southeastern Attica, Greece, the extraction
Anna Lagia, Sydney Patterson, Isabelle De Groote   +2 more
doaj   +1 more source

Sulfobetaine-Based Homo- and Copolymers by RAFT: Cross-Linked Micelles and Aqueous Solution Properties

, 2022
Seda Gürdap, Nazende Nur Bayram, İsmail Alper İşoğlu, Sevil Dinçer   +3 more
openalex   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Homo sapiens (2501.1rp49) – cranial fragment

, 2020
rla-archaeology
openalex   +1 more source

The state of modern economics : Is rational man extinct? [PDF]

Searching for Homo EconomicusEconomics ; Rational expectations (Economic theory)
Stephen Slivinski
core