Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Structural evolution and stabilities of (CuIn) n Te2 and ((CuIn) n Te2)- (n = 1-8) clusters via DFT study. [PDF]
Gerezgiher KG +4 more
europepmc +1 more source
New institutionalism at the heuristic frames - historical roots, social theories, research methods [recenzja książki]: Chmielewski, Piotr. 2011. Homo agens : instytucjonalizm w naukach społecznych. Warszawa : Wydawnictwo Poltext [PDF]
Katarzyna Leszczyńska
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
<i>In Silico</i> Perspective on Avobenzone, Octisalate, Octocrylene, Homosalate, and Bemotrizinol as Organic UV Filters Using DFT, TD-DFT, and Molecular Dynamics. [PDF]
Rigoni ME, de Lazaro SR, de Lara LS.
europepmc +1 more source
Giovannangiola Tarugi (book editor) +1 more
openaire +2 more sources
Homo Fictor (essais), suivi de " Étude et exploration du genre de l'essai et de la figure d'auteur dans Yucca Mountain de John D'Agata " [PDF]
Yohan Proulx
openalex

