Results 141 to 150 of about 143,735 (277)

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley   +2 more sources

Is There Any Difference in the Plasma Homocysteine Levels of Diabetes Mellitus Type Ii Patients, Impaired Glucose Tolerance Subjects and Normal People?

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2005
Introduction: Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease in diabetic patients. The aim of this study was to determine plasma homocysteine levels in diabetics and compare with control persons and also evaluation of
M Amini, A Kachoie, H Rezvanian, A Amin-Alroaaya, M Mohammadi   +4 more
doaj  

Elevated homocysteine is negatively correlated with plasma cystathionine β‐synthase activity in givosiran‐treated patients

JIMD Reports
Givosiran is a subcutaneously administered, liver‐targeted RNA interference (RNAi) therapeutic that has been approved for treating acute hepatic porphyria (AHP).
Mark A. Keibler, Gautham V. Sridharan, Marianne T. Sweetser, Simina Ticau   +3 more
doaj   +1 more source

Article Commentary: Retinal Ganglion Cell Loss in Diabetes Associated with Elevated Homocysteine

Ophthalmology and Eye Diseases, 2009
A number of studies have suggested that homocysteine may be a contributing factor to development of retinopathy in diabetic patients based on observed correlations between elevated homocysteine levels and the presence of retinopathy.
Kenneth S. Shindler
doaj   +1 more source

Serum homocysteine level and protein intake are related to risk of microalbuminuria: The Hoorn Study [PDF]

, 1998
Ellen K. Hoogeveen, Pieter J. Kostense, Agnes Jager, Robert J. Heine, Cornelis Jakobs, L.M. Bouter, A. J. M. Donker, Coen D.A. Stehouwer   +7 more
openalex   +1 more source

Effect of vitamin B therapy and polymorphism of MS & CBS gene on homocysteine, cardiovascular events in ischemic stroke: A randomized controlled trial [PDF]

, 2022
Ms. Neetu Kataria, Prof. Vasantha C.kalyani, Mritunjai Kumar, Anissa Atif Mirza, Shashi Ranjan, Mr.Nitesh Kumar, Yogesh Bahurupi, Prof.Vivekanandhan S, Anil Kumar Sharma   +8 more
openalex   +1 more source

The Correlations of Clinical Outcomes and Vascular Morphology With Infarct Patterns in Middle Cerebral Arterial Occlusion

Brain and Behavior, Volume 16, Issue 2, February 2026.
For stroke caused by large vessel occlusion in M1 segment of middle cerebral artery (MCA), a tortuous and long M1 segment of contralateral MCA (cMCA) correlates with the onset of borderzone infarct. In those with a less tortuous cMCA‐M1 segment, a thin and short M1 segment correlates with large infarct.
ZhiRong Cai, Yuan Chen, ShaoQing Pei, Yue He, YaNan Zhu, Rui Zhang, JingWei Lin, Yi Yang, Ying Zhu   +8 more
wiley   +1 more source

Decreased serum homocysteine levels after micronutrient supplementation in older people [PDF]

Universa Medicina, 2010
Aging is associated with a gradual impairment in cognitive function. The elderly also show a high prevalence of undernutrition, whereas nutrition plays an important role in the metabolism of neuronal cells and enzymes.
Pusparini
doaj  

Effect of non‐surgical periodontal therapy on plasma homocysteine levels in Indian population with chronic periodontitis: a pilot study [PDF]

, 2015
Smiti Bhardwaj, M. L. V. Prabhuji, Bangalore Vardhan Karthikeyan   +2 more
openalex   +1 more source