Results 121 to 130 of about 90,248 (215)
Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11808-11820, December 2026.ABSTRACT Aims Metformin, the first‐line treatment for Type 2 diabetes mellitus (T2DM), may be neuroprotective but also lowers serum vitamin B12 by ~19%, raising concern that B12 depletion could offset this benefit. We used modern exploratory causal mediation methods in a nationally representative sample to test whether vitamin B12 and methylmalonic ...
Danial Fotros +2 more
wiley +1 more source
CORRELATION BETWEEN TOTAL PLASMA HOMOCYSTEINE LEVEL AND GRADING OF CORONARY ARTERY DISEASE
Acta Medica Iranica, 2008 Elevated total plasma homocysteine (tHcy) levels constitute a risk factor for coronary artery disease (CAD). A possible relationship was investigated between admission plasma homocysteine level and the angiographic severity and extension of coronary ...
S. J. Mirhoseini +6 more
doaj
Convulsive properties of D,L homocysteine and D,L homocysteine thiolactone in adult rats
, 2011 Introduction: Hyperhomocysteinemia is related to epileptogenesis and suboptimal control of seizures in the patients with epilepsy. Available data suggest that homocysteine can be harmful to human cells because of its metabolic conversion to homocysteine
Hrncic, D +3 more
core +1 more source
Rapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.ABSTRACT Rationale Non‐reduced trypsin digestion of therapeutic antibodies can generate large disulfide‐linked peptide complexes that exhibit poor chromatographic and mass spectrometric performance. This limits the confident characterization of posttranslational modifications (PTMs) in specific antibody regions, such as the heavy‐chain constant region ...
Nanna Sofie Eskesen +10 more
wiley +1 more source
Homocysteine and endothelial dysfunction
, 2007 This chapter contains sections titled: Introduction Terminology, biochemistry, distribution, and metabolism of homocysteine Normal and pathological levels of homocysteine: classification and incidence of hyperhomocysteinemia ...
Rosalinda Madonna, Raffaele De Caterina
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ChemMedChem, Volume 21, Issue 21, 12 November 2026.Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai +5 more
wiley +1 more source
Is Homocysteine a pro-oxidant ?
, 2001 High plasma homocysteine concentrations have been found to be associated with atherosclerosis and thrombosis of arteries and deep veins. The oxidative damage mediated by hydrogen peroxide production during the metal-catalyzed oxidation of homocysteine is
Giardina, Bruno +5 more
core +1 more source
Arthritis Care &Research, Volume 78, Issue 11, Page 1691-1700, November 2026.Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli +10 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005 Background and Objective: Homocysteine is an amino acid with a free thiol (Sulphydryl) group and is an intermediate formed during the metabolism of methionine to cysteine.
F Darabi +4 more
doaj
Vitamin B12, folate, and homocysteine levels in patients with obsessive–compulsive disorder
, 2014 Nuray Türksoy,1 Rabia Bilici,2 Altan Yalçiner,3 Y Özay Özdemir,2 Ibrahim Örnek,4 Ali Evren Tufan,5 Ayşe Kara6 1Simurg Psychiatry and Psychotherapy Center, Istanbul, 2Erenköy State Hospital for Psychiatric and Neurological
Bilici R +6 more
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