Results 141 to 150 of about 124,435 (251)
National Journal of Medical Research, 2012 Introduction: Abnormal Homocysteine (HCY) level appear to contribute to atherosclerosis by direct toxic effect that damages the arterial linings, interfering with the clotting factors and oxidation of LDL.
Asutosh P Chauhan +3 more
doaj
Pregnancy, Volume 2, Issue 3, May 2026.Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld +5 more
wiley +1 more source
Substrate selectivity of human histidine methyltransferase METTL9
Protein Science, Volume 35, Issue 5, May 2026.Abstract Methylation of histidine residues in zinc transporters by histidine methyltransferase METTL9 plays an important role in modulating their metal‐binding properties. Here, we report synthetic, enzymatic, and computational studies on human METTL9‐catalyzed Nπ‐methylation of His375 in zinc transporter SLC39A5‐derived peptides in which the histidine
Sadaf Ahmad +7 more
wiley +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
Aging Cell, Volume 25, Issue 5, May 2026.Fecal microbiota transplantation from elderly donors with Alzheimer's disease, type 2 diabetes, or both conditions into antibiotic‐treated mice revealed that comorbid microbiota produce the most severe dysbiosis and strongest suppression of hippocampal neurotrophic gene expression.
Alessandro Atzeni +16 more
wiley +1 more source
Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging
Aging Cell, Volume 25, Issue 5, May 2026.This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong +7 more
wiley +1 more source
An atlas of plant selenium metabolism
New Phytologist, Volume 250, Issue 4, Page 2041-2060, May 2026.Summary Selenium (Se) is not only a rare and toxic element but also an essential micronutrient for humans and animals that is often in short supply. Terrestrial plants do not require Se, but it can have growth‐promoting or negative effects, depending on the exposure level.
Jeroen van der Woude +3 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005 Background and Objective: Homocysteine is an amino acid with a free thiol (Sulphydryl) group and is an intermediate formed during the metabolism of methionine to cysteine.
F Darabi +4 more
doaj
Structure, function and substrate preferences of archaeal S-adenosyl-l-homocysteine hydrolases
Communications BiologyS-Adenosyl-l-homocysteine hydrolase (SAHH) reversibly cleaves S-adenosyl-l-homocysteine, the product of S-adenosyl-l-methionine-dependent methylation reactions.
Lars-Hendrik Koeppl +4 more
doaj +1 more source