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Best Practice & Research Clinical Obstetrics & Gynaecology, 2003
Homocysteine is an amino acid that is involved in several key metabolic processes, including the methylation and sulphuration pathways. Blood concentrations of homocysteine are determined by various dietary factors, including folic acid and vitamin B(12), by alteration in physiology, such as renal impairment, and by variation in the activity of enzymes
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Homocysteine is an amino acid that is involved in several key metabolic processes, including the methylation and sulphuration pathways. Blood concentrations of homocysteine are determined by various dietary factors, including folic acid and vitamin B(12), by alteration in physiology, such as renal impairment, and by variation in the activity of enzymes
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Homocysteine measurement by Vitros® Microtip homocysteine assay
Clinical Chemical Laboratory Medicine, 2008Elevated circulating total homocysteine is an independent vascular risk factor. Enzymatic homocysteine measurements represent an alternative to HPLC- or immunochemistry-based assays, suitable for automation. Here, we report on analytical performance of a commercial cystathionine beta-synthase-based assay, for use on Vitros automated analyzers.Linear ...
Geert A, Martens +5 more
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New England Journal of Medicine, 2002
Homocysteine is a simple amino acid that has recently received a great deal of attention as a risk factor for atherothrombotic vascular disease. There is reasonably compelling epidemiologic evidence of an association between the plasma homocysteine level and the risk of vascular disease in the coronary, carotid, and peripheral circulations.
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Homocysteine is a simple amino acid that has recently received a great deal of attention as a risk factor for atherothrombotic vascular disease. There is reasonably compelling epidemiologic evidence of an association between the plasma homocysteine level and the risk of vascular disease in the coronary, carotid, and peripheral circulations.
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Annual Review of Nutrition, 1999
▪ Abstract Homocysteine is a sulfur amino acid whose metabolism stands at the intersection of two pathways: remethylation to methionine, which requires folate and vitamin B12 (or betaine in an alternative reaction); and transsulfuration to cystathionine, which requires pyridoxal-5′-phosphate.
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▪ Abstract Homocysteine is a sulfur amino acid whose metabolism stands at the intersection of two pathways: remethylation to methionine, which requires folate and vitamin B12 (or betaine in an alternative reaction); and transsulfuration to cystathionine, which requires pyridoxal-5′-phosphate.
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Clinical Chemistry and Laboratory Medicine, 2003
Indirect pathways, involving homocysteine (Hcy)-thiolactone and S-nitroso-Hcy, allow incorporation of Hcy into protein. Hcy-thiolactone, synthesized by methionyl-tRNA synthetase in all organisms investigated, including human, modifies proteins post-translationally by forming adducts in which Hcy is linked by amide bonds to epsilon-amino group of ...
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Indirect pathways, involving homocysteine (Hcy)-thiolactone and S-nitroso-Hcy, allow incorporation of Hcy into protein. Hcy-thiolactone, synthesized by methionyl-tRNA synthetase in all organisms investigated, including human, modifies proteins post-translationally by forming adducts in which Hcy is linked by amide bonds to epsilon-amino group of ...
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Homocystein – Ist die Homocystein-These tot?
Erfahrungsheilkunde, 2010Some years ago, scientists discovered that homocysteine in the blood is a cardiovascular risk factor. This has been confirmed by fundamental experiments and epidemiologic studies. The studies HOPE-2 and NORVIT seem to have refuted the thesis. A critical analysis of the examinations suggests, that a lowering of the homocysteine value with vitamin B ...
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Serum Total Homocysteine and Coronary Heart Disease
International Journal of Epidemiology, 1995Kaare Harald Bønaa +2 more
exaly