Results 121 to 130 of about 1,318,508 (390)

Cross Immunity of a Sonicated Trivalent Avian Colibacillosis Vaccine to Pathogenic Escherichia coli O26 and O78 Strains in Broiler Chickens [PDF]

The Iranian Journal of Veterinary Science and Technology
Colibacillosis outbreaks are a global issue affecting the poultry industry. There is no cross-immunity among the strains of APEC. If a vaccine induces cross-immunity, it will play a key role in preventing colibacillosis.
Sima Alempour Rajabi, Zolfaghar Rajabi
doaj   +1 more source

Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair

Nature, 2015
Large-scale genomic studies have shown that half of epithelial ovarian cancers (EOCs) have alterations in genes regulating homologous recombination (HR) repair.
Raphael Ceccaldi, Jessica C. Liu, R. Amunugama, Ildikó Hajdú, Benjamin Primack, Mark I. R. Petalcorin, Kevin W. O’Connor, P. Konstantinopoulos, S. Elledge, S. Boulton, T. Yusufzai, A. D’Andrea   +11 more
semanticscholar   +1 more source

Simultaneous precise editing of multiple genes in human cells

, 2019
. When double-strand breaks are introduced in a genome by CRISPR they are repaired either by non-homologous end joining (NHEJ), which often results ...
Chintalapati, M., Kanis, P., Macak, D., Maricic, T., Pääbo, S., Riesenberg, S.   +5 more
core   +1 more source

Pattern-equivariant homology [PDF]

Algebraic & Geometric Topology, 2017
41 pages, 4 ...
openaire   +6 more sources

Symmetric Homology is Representation Homology

, 2022
Symmetric homology is a natural generalization of cyclic homology, in which symmetric groups play the role of cyclic groups. In the case of associative algebras, the symmetric homology theory was introduced by Z. Fiedorowicz \cite{F} and was further developed in the work of S. Ault \cite{Au1, Au2}. In this paper, we show that, for algebras defined over
Berest, Yuri, Ramadoss, Ajay C.
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Moringa oleifera Alkaloids Inhibited PC3 Cells Growth and Migration Through the COX-2 Mediated Wnt/β-Catenin Signaling Pathway

Frontiers in Pharmacology, 2020
Moringa oleifera Lam. (M. oleifera) is valuable plant distributed in many tropical and subtropical countries. It has a number of medicinal uses and is highly nutritious. M.
Jing Xie, Jing Xie, Feng-xian Luo, Feng-xian Luo, Chong-ying Shi, Chong-ying Shi, Wei-wei Jiang, Ying-yan Qian, Ying-yan Qian, Ming-rong Yang, Ming-rong Yang, Shuang Song, Shuang Song, Tian-yi Dai, Lei Peng, Xiao-yu Gao, Liang Tao, Liang Tao, Yang Tian, Yang Tian, Yang Tian, Jun Sheng   +21 more
doaj   +1 more source

Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes

Nature Communications, 2017
BRCA1 and BRCA2 are involved in homologous recombination (HR) DNA repair and are germ-line cancer pre-disposition genes that result in a syndrome of hereditary breast and ovarian cancer (HBOC).
N. Riaz, P. Blecua, R. Lim, R. Shen, D. Higginson, Nils Weinhold, L. Norton, B. Weigelt, S. Powell, J. Reis-Filho   +9 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células dendríticas Alogenic islet transplantation on the rat liver after alogenic dendritic cells injection in the thymus

Arquivos de Gastroenterologia, 2005
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib, Apostolos Papalois, Ingrid G. M. Brons, Roy Y. Calne   +3 more
doaj   +1 more source