Results 181 to 190 of about 1,306,827 (384)

Two-dimensional iodopeptide mapping demonstrates that erythrocyte Rh D, c, and E polypeptides are structurally homologous but nonidentical [PDF]

, 1988
Dominique Blanchard, C Bloy, Patricia Hermand, JP Cartron, AM Saboori, BL Smith, Peter Agre   +6 more
openalex   +1 more source

Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80 [PDF]

, 2020
Jason M. Keil, Daniel Z. Doyle, Adel Qalieh, Mandy M. Lam, Owen H. Funk, Yaman Qalieh, Lei Shi, Nitesh Mohan, Alice Sorel, Kenneth Y. Kwan   +9 more
openalex   +1 more source

Engineering the Link: From Genome Interaction Maps to Functional Insight

Advanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann, Dominik Niopek   +5 more
wiley   +1 more source

Introducing the CRISPR/Cas9 cytosine base editor toolbox ‘LeishBASEedit’ – Gene editing and high-throughput screening in Leishmania without requiring DNA double-strand breaks, homologous recombination or donor DNA [PDF]

, 2022
Tom Beneke, Markus Engstler
openalex   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Moving forward one step back at a time: reversibility during homologous recombination

, 2019
Aurèle Piazza, Wolf‐Dietrich Heyer
openalex   +2 more sources

The association of tryptophan synthetase subunits fromEscherichia coliandSalmonella typhimuriumin homologous and heterologous combinations [PDF]

, 1976
Ralph F. DiCamelli, Elias Balbinder
openalex   +1 more source

Fluorophobic Effect Enables Selective Detection of PFAS in Water with Electrolyte‐Gated Organic Transistors

Advanced Functional Materials, EarlyView.
PerFluoroAlkyl Substances (PFAS) are responsible of major and persistent environmental pollution worldwide. This work demonstrates an ultra‐sensitive sensor for PFAS based on an organic transistor whose gate is functionalized with a binary self‐assembled monolayer containing a perfluorinated molecule.
Rian Zanotti, Marcello Berto, Matteo Sensi, Alessandro Paradisi, Eleonora Veronese, Lucia Pasquato, Carlo Augusto Bortolotti, Pierangelo Metrangolo, Fabio Biscarini   +8 more
wiley   +1 more source

Identification of a Novel Gene Model-Based Homologous Recombination Deficiency Score to Improve Survival Prediction of TNBC. [PDF]

, 2021
Wenxiang Zhang, Bolun Ai, Xiangyi Kong, Xiangyu Wang, Jie Zhai, Ran Gao, Yihang Qi, Qiang Liu, Mengliu Zhu, Yingpeng Ren, Yi Fang, Jing Wang   +11 more
openalex   +1 more source

Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer

Clinical Cancer Research, 2016
M. Telli, K. Timms, J. Reid, B. Hennessy, G. Mills, K. Jensen, Z. Szallasi, W. Barry, E. Winer, N. Tung, S. Isakoff, P. Ryan, April Greene-Colozzi, A. Gutin, Zaina Sangale, D. Iliev, C. Neff, V. Abkevich, Joshua T. Jones, J. Lanchbury, A. Hartman, J. Garber, J. Ford, D. Silver, A. Richardson   +24 more
semanticscholar   +1 more source