Results 21 to 30 of about 621,494 (219)

Effects of a canned infant juice auxiliary food on acute inflammation in young mice and antioxidant activity

Shipin yu jixie
ObjectiveTo investigate the effects of an infant juice canned auxiliary food on acute inflammation and antioxidant activity in young mice.Methods70 mice were divided into blank group, model group, low dose group (8.697 9 g/kg), middle dose group (17.395 ...
DAI Zhiyong, DENG Bin, LI Jiani, XIAO Zuowei, ZHOU Yimiao   +4 more
doaj   +1 more source

Exploring the Mechanism of Action of Sea Buckthorn in the Treatment of Alcoholic Liver Injury Based on Network Pharmacology

Shipin gongye ke-ji
Objective: To predict the mechanism of sea buckthorn in the treatment of alcoholic liver injury based on network pharmacology, and to verify the efficacy of sea buckthorn in the treatment of alcoholic liver injury by establishing an animal model of ...
Bin DENG, Jie CHEN, Xiang LI, Kexuan LOU, Liquan ZHOU, Yimiao ZHOU, Zuowei XIAO   +6 more
doaj   +1 more source

Safety and immunogenicity of heterologous and homologous inactivated and adenoviral-vectored COVID-19 vaccine regimens in healthy adults: a prospective cohort study

Human Vaccines & Immunotherapeutics, 2022
In light of intermittent supply shortages of individual vaccines and evidence of rare but serious adverse events after vaccination, heterologous regimens for COVID-19 vaccines have gained significant interest. This study aims to assess the reactogenicity
Nasamon Wanlapakorn, Nungruthai Suntronwong, Harit Phowatthanasathian, Ritthideach Yorsaeng, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Chompoonut Auphimai, Donchida Srimuan, Thaksaporn Thatsanatorn, Suvichada Assawakosri, Sitthichai Kanokudom, Yong Poovorawan   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Virulence Phenotyping and Molecular Characterization of a New Virulence Type of Pyrenophora tritici-repentis the Causal Agent of Tan Spot

The Plant Pathology Journal, 2018
Pyrenophoratritici-repentis is the causal agent of tan spot. According to their ability to produce necrosis and/or chlorosis on a set of four differential bread wheats, the isolates of this fungus are currently grouped into eight races.
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Preparation, characterization, assembly, and stability of walnut peptide - zinc complexes and its ability to promote zinc transport in Caco-2 cells

Food Chemistry: X
Walnut peptides (WP) are promising metal-ion carriers that are expected to improve the bioavailability of dietary micronutrients. In this study, walnut peptide zinc complexes (WP-Zn), a novel zinc supplement differentiated from conventional zinc salts ...
Dong Lin, Liyun Zhang, Hongdan Li, Qin Liu, Yongqing Zhang, Yalin Ni, Meihan Liu, Su Xu   +7 more
doaj   +1 more source

Multi-wavelength fluorescence polarization immunoassays for simultaneous detection of amantadine and ribavirin in chicken and human serum

Food and Agricultural Immunology, 2021
In this study, a homologous multi-wavelength fluorescence polarization immunoassays (MWFPIA) for rapid determination of amantadine (AMD) and ribavirin (RVB) simultaneously was established.
Liuchuan Guo, Meixuan Liu, Suxia Zhang, Zhanhui Wang, Xuezhi Yu   +4 more
doaj   +1 more source