Results 61 to 70 of about 1,306,827 (384)
High fidelity of RecA-catalyzed recombination: a watchdog of genetic diversity [PDF]
, 2006 Homologous recombination plays a key role in generating genetic diversity, while maintaining protein functionality. The mechanisms by which RecA enables a single-stranded segment of DNA to recognize a homologous tract within a whole genome are poorly ...
Sagi, Dror, Stavans, Joel, Tlusty, Tsvi
core +6 more sources
Nature Biotechnology, 2015 Methods to introduce targeted double-strand breaks (DSBs) into DNA enable precise genome editing by increasing the rate at which externally supplied DNA fragments are incorporated into the genome through homologous recombination.
T. Maruyama +5 more
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Revista Brasileira de Ginecologia e Obstetrícia, 2007 OBJETIVO: avaliar resultados da neovaginoplastia com utilização de enxerto amniótico humano em pacientes portadoras da síndrome de Mayer-Rokitansky-Küster-Hauser (MRKH).
Bruno Ramalho de Carvalho +5 more
doaj +1 more source
Homological properties of persistent homology
Journal of Algebra and Its ApplicationsIn this paper, we investigate to what extent persistent homology benefits from the properties of a homology theory. We show that persistent homology benefits from a Mayer–Vietoris sequence and a long exact sequence for a pair if one works with graded persistence modules.
Hani̇fe Varlı +2 more
openaire +4 more sources
Computational Geometry, 2007 The paper is focused on the so called localization problem which can be characterised as a determination of certain topological features within a space. While the topology, and especially the homology gives the information about the existence of the topological features and attributes, the information about their location cannot be directly known.
Zomorodian, Afra, Carlsson, Gunnar
openaire +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Somatic Pairing in Drosophila virilis Mitosis [PDF]
, 1975 In neuroblast cells homologous chromosomes tend to pair during prophase of mitosis. Heterochromatic elements of homologous chromosomes are widely separated in very early prophase, at which time the euchromatin is poorly stained.
Guest, William C.
core +2 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Analytic Inversion of Emission Lines of Arbitrary Optical Depth for the Structure of Supernova Ejecta [PDF]
, 2000 We derive a method for inverting emission line profiles formed in supernova ejecta. The derivation assumes spherical symmetry and homologous expansion (i.e., $v(r) \propto r$), is analytic, and even takes account of occultation by a pseudo-photosphere ...
Adam Fisher +17 more
core +2 more sources