Homologous chromosome pairing starts at the ends. [PDF]
De Jaeger-Braet J.
europepmc +3 more sources
Site-Specific Sequence Exchange Between Homologous and Non-homologous Chromosomes [PDF]
Transgene integration typically takes place in an easy-to-transform laboratory variety before the transformation event is introgressed through backcrosses to elite cultivars. As new traits are added to existing transgenic lines, site-specific integration can stack new transgenes into a previously created transgenic locus.
Qian Yin, Qian Yin, Ruyu Li, David W. Ow
openaire +3 more sources
Modeling homologous chromosome recognition via nonspecific interactions. [PDF]
In many organisms, most notably Drosophila , homologous chromosomes associate in somatic cells, a phenomenon known as somatic pairing, which takes place without double strand breaks or strand invasion, thus requiring some other mechanism for homologs to recognize each other.
Marshall WF, Fung JC.
europepmc +5 more sources
Dynamics of rye chromosome 1R regions with high or low crossover frequency in homology search and synapsis development. [PDF]
In many organisms, homologous pairing and synapsis depend on the meiotic recombination machinery that repairs double-strand DNA breaks (DSBs) produced at the onset of meiosis.
Nohelia T Valenzuela +2 more
doaj +1 more source
Chromosomally-retained RNA mediates homologous pairing [PDF]
Pairing and recombination of homologous chromosomes are essential for ensuring correct segregation of chromosomes in meiosis. In S. pombe, chromosomes are first bundled at the telomeres (forming a telomere bouquet) and then aligned by oscillatory movement of the elongated "horsetail" nucleus.
Ding, Da-Qiao +2 more
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A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco +9 more
core +3 more sources
Chromosome painting reveals asynaptic full alignment of homologs and HIM-8-dependent remodeling of X chromosome territories during Caenorhabditis elegans meiosis. [PDF]
During early meiotic prophase, a nucleus-wide reorganization leads to sorting of chromosomes into homologous pairs and to establishing associations between homologous chromosomes along their entire lengths.
Kentaro Nabeshima +2 more
doaj +1 more source
Natural Chromosome-Chromid Fusion across rRNA Operons in a Burkholderiaceae Bacterium
Chromids (secondary chromosomes) in bacterial genomes that are present in addition to the main chromosome appear to be evolutionarily conserved in some specific bacterial groups.
Jiro F. Mori, Robert A. Kanaly
doaj +1 more source
Pushing the (nuclear) envelope into meiosis. [PDF]
A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core +1 more source
Distance between homologous chromosomes results from chromosome positioning constraints [PDF]
The organization of chromosomes is important for various biological processes and is involved in the formation of rearrangements often observed in cancer. In mammals, chromosomes are organized in territories that are radially positioned in the nucleus. However, it remains unclear whether chromosomes are organized relative to each other.
Heride, Claire +7 more
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