Results 21 to 30 of about 191,808 (260)

Improved reconstruction and comparative analysis of chromosome 12 to rectify Mis-assemblies in Gossypium arboreum

BMC Genomics, 2020
Background Genome sequencing technologies have been improved at an exponential pace but precise chromosome-scale genome assembly still remains a great challenge. The draft genome of cultivated G.
Javaria Ashraf, Dongyun Zuo, Hailiang Cheng, Waqas Malik, Qiaolian Wang, Youping Zhang, Muhammad Ali Abid, Qiuhong Yang, Xiaoxu Feng, John Z. Yu, Guoli Song   +10 more
doaj   +1 more source

Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. [PDF]

PLoS Genetics, 2008
Several meiotic processes ensure faithful chromosome segregation to create haploid gametes. Errors to any one of these processes can lead to zygotic aneuploidy with the potential for developmental abnormalities.
Tom A Hartl, Sarah J Sweeney, Peter J Knepler, Giovanni Bosco   +3 more
doaj   +1 more source

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination

Frontiers in Plant Science, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio, Heïdi Serra, Pierre Sourdille, James D. Higgins   +3 more
doaj   +1 more source

Meiotic telomeres: a matchmaker for homologous chromosomes [PDF]

Genes to Cells, 1998
Telomeres, with their special structures and special schemes of synthesis, are essential for protecting the ends of eukaryotic linear chromosomes during cell proliferation. In addition to this basic function, the meiosis‐specific functions of telomeres have long been inferred from the cytological observations of characteristic chromosome configurations
openaire   +2 more sources

Mouse oocytes carrying metacentric Robertsonian chromosomes have fewer crossover sites and higher aneuploidy rates than oocytes carrying acrocentric chromosomes alone

Scientific Reports, 2022
Meiotic homologous recombination during fetal development dictates proper chromosome segregation in adult mammalian oocytes. Successful homologous synapsis and recombination during Meiotic Prophase I (MPI) depends on telomere-led chromosome movement ...
Parinaz Kazemi, Teruko Taketo
doaj   +1 more source

The courtship choreography of homologous chromosomes: timing and mechanisms of DSB-independent pairing

Frontiers in Cell and Developmental Biology, 2023
Meiosis involves deep changes in the spatial organisation and interactions of chromosomes enabling the two primary functions of this process: increasing genetic diversity and reducing ploidy level.
Mireia Solé, Álvaro Pascual, Ester Anton, Joan Blanco, Zaida Sarrate   +4 more
doaj   +1 more source

Chromosomally-retained RNA mediates homologous pairing [PDF]

Nucleus, 2012
Pairing and recombination of homologous chromosomes are essential for ensuring correct segregation of chromosomes in meiosis. In S. pombe, chromosomes are first bundled at the telomeres (forming a telomere bouquet) and then aligned by oscillatory movement of the elongated "horsetail" nucleus.
Ding, Da-Qiao, Haraguchi, Tokuko, Hiraoka, Yasushi   +2 more
openaire   +2 more sources

Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis. [PDF]

PLoS Genetics, 2013
Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of recombination, provide the physical link that holds the homologs together as a pair, facilitating ...
Michel F Guiraldelli, Craig Eyster, Joseph L Wilkerson, Michael E Dresser, Roberto J Pezza   +4 more
doaj   +1 more source

Control of homologous chromosome division in the mammalian oocyte [PDF]

Molecular Human Reproduction, 2009
Homologous chromosomes are segregated during the first meiotic division (meiosis I). Unfortunately, human oocytes are particularly susceptible to mis-segregation errors, so generating aneuploid, often non-viable, embryos. Here we review the cell biology of meiosis I and how homolog disjunction is regulated for mammalian oocytes.
Holt, Janet E., Jones, Keith T.
openaire   +2 more sources

Agent-based modeling of nuclear chromosome ensembles identifies determinants of homolog pairing during meiosis.

PLoS Computational Biology
During meiosis, pairing of homologous chromosomes (homologs) ensures the formation of haploid gametes from diploid precursor cells, a prerequisite for sexual reproduction.
Ariana Chriss, G Valentin Börner, Shawn D Ryan   +2 more
doaj   +1 more source