Results 231 to 240 of about 1,025,592 (331)

The Synaptinemal Complex in Homologous and Nonhomologous Pairing of Chromosomes

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1974
C. B. Gillies   +2 more
openaire   +3 more sources

Clinical validation of a DNA methylation biomarker associated with overall survival of relapsed ovarian cancer patients

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Most patients with ovarian cancer (OC) relapse after first‐line chemotherapy, and prognosis with second‐line treatment depends largely on the platinum‐free interval. However, reliable biomarkers to predict response to second‐line therapy remain lacking.
Muhammad Habiburrahman   +7 more
wiley   +1 more source

Gene order and recombination rate in homologous chromosome regions of the chicken and a passerine bird.

open access: yesMolecular biology and evolution, 2007
D. Dawson   +5 more
semanticscholar   +1 more source

A Case of Metastatic Castration‐Resistant Prostate Cancer With RAD54L Mutation Responding to Niraparib

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction A certain proportion of prostate cancers have alterations in homologous recombination repair (HRR)‐ related genes. poly ADP‐ribose polymerase (PARP) inhibitors have been approved for metastatic castration‐resistant prostate cancer (mCRPC) with mutations in the BRCA1/2 gene.
Yusuke Sato   +9 more
wiley   +1 more source

Isodicentric Y chromosome with SRY duplication in a female with complete gonadal dysgenesis. [PDF]

open access: yesMol Cytogenet
Salmaninejad A   +6 more
europepmc   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado   +9 more
wiley   +1 more source

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