Results 281 to 290 of about 1,130,741 (368)

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Determining Zygosity With Multiplex Kompetitive Allele-Specific PCR (mxKASP) Genotyping. [PDF]

Ecol Evol
Meilink WRM, de Visser MC, Theodoropoulos A, Fahrbach M, Wielstra B.   +4 more
europepmc   +1 more source

Meiotic Deletion at the BUF1 Locus of the Fungus Magnaporthe grisea Is Controlled by Interaction With the Homologous Chromosome

, 2002
Mark Farman
openalex   +2 more sources

Neuroprotective Potential of the Flavonoids Quercetin and Epicatechin in a C. elegans Tauopathy Model

Molecular Nutrition &Food Research, EarlyView.
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García, Begoña Ayuda‐Durán, Susana González‐Manzano, Celestino Santos‐Buelga, Ana M. González‐Paramás   +4 more
wiley   +1 more source

Genetic Diagnosis and Clinical Features of Fetuses With Congenital Diaphragmatic Hernia

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Congenital diaphragmatic hernia (CDH) is a rare abnormality with highly heterogeneous genetic causes. This study investigated chromosomal and monogenic abnormalities in fetal CDH patients and evaluated the efficacy of chromosomal microarray analysis (CMA) and whole‐exome sequencing (WES) for genetic diagnosis.
Yan Lü, Yi Yu, Jiazhen Chang, Mengmeng Li, Xueting Yang, Xiya Zhou, Na Hao, Hua Meng, Zhenghong Li, Lishuang Ma, Hui You, Shan Jian, Ying Wang, Shengjie Li, Yiqing Yu, Kaili Yin, Mingming Wang, Yulin Jiang, Qingwei Qi   +18 more
wiley   +1 more source

Hypothesis that ancestral eukaryotes sexually proliferated without kinetochores or mitosis.

J Cell Sci
Akiyoshi B.
europepmc   +1 more source

Comparative transcriptome analysis reveals key genes associated with meiotic stability and high seed setting rate in tetraploid rice. [PDF]

BMC Plant Biol
Lv P, Wang M, Qiu R, Yao C, Fang M, Xing Y, Zhang X, He Y, Cai D, Song Z.   +9 more
europepmc   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Pairing between homologous sequences on the X and chromosome 3 in Drosophila male meiosis. [PDF]

Genetics
Hylton CA, Hansen K, Tomkiel Dean JE.
europepmc   +1 more source

The Homologous Chromosome Is an Effective Template for the Repair of Mitotic DNA Double-Strand Breaks in Drosophila

, 2003
Yikang S. Rong, Kent G. Golic
openalex   +2 more sources