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Homologous chromosome pairing in Schizosaccharomyces pombe
Yeast, 2006AbstractHomologous chromosome pairing is a central feature of meiosis I, contributing to the correct segregation of chromosomes during meiosis. The fission yeast, Schizosaccharomyces pombe, has been widely used to study meiotic chromosome dynamics, partly because studies in this yeast are simplified due to the lack of post‐pairing synaptic structures ...
Jennifer L, Wells +2 more
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The cytogenetics of homologous chromosome pairing in meiosis in plants
Cytogenetic and Genome Research, 2008Three activities hallmark meiotic cell division: homologous chromosome pairing, synapsis, and recombination. Recombination and synapsis are well-studied but homologous pairing still holds many black boxes. In the past several years, many studies in plants have yielded insights into the mechanisms of chromosome pairing interactions.
C G, Bozza, W P, Pawlowski
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A study of homologous chromosomes using a morphometric approach
Genome, 1993A previous study of 100 karyotyped metaphase cells has demonstrated the utility of a graphic arts tool in deriving chromosome measurements for relative length determination. In the present study we utilize this same approach to address the question: "What are the average differences in relative lengths between apparently normal homologous chromosomes?"
H F, Mark +6 more
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Homologous Recombination Using Bacterial Artificial Chromosomes
Cold Spring Harbor Protocols, 2015This protocol introduces the technique of homologous recombination in bacteria to insert a linear DNA fragment into bacterial artificial chromosomes (BACs). Homologous recombination allows the modification of large DNA molecules, in contrast with conventional restriction endonuclease-based strategies, which cleave large DNAs into numerous fragments and
Cary, Lai +2 more
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Human chromosome 9 pericentric homologies: implications for chromosome 9 heteromorphisms
Cytogenetic and Genome Research, 1998Pericentromeric polymorphisms of chromosome 9 include variations in the size of heterochromatin, pericentric inversions, and, more rarely, additional C-band-negative, G-band-positive material in either the proximal short arm or long arm or within the heterochromatin.
J P, Park +4 more
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Initiation of homologous chromosome pairing during meiosis
Biochemical Society Transactions, 2006Following pre-meiotic DNA replication, homologous chromosomes must be paired and become tightly linked to ensure reductional segregation during meiosis I. Therefore initiation of homologous chromosome pairing is vital for meiosis to proceed correctly. A number of factors contribute to the initiation of homologous chromosome pairing including telomere ...
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Machine learning approach for homolog chromosome classification
International Journal of Imaging Systems and Technology, 2018AbstractAutomated analysis of human chromosomes is a necessary procedure to attain karyotyping and it is highly effective in cytology analysis to detect birth defects in metaspread chromosomes. In this, chromosomes are partitioned into “abnormal” and “normal” categories.
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Homologous pairing and chromosome dynamics in meiosis and mitosis
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2004Pairing of homologous chromosomes is an essential feature of meiosis, acting to promote high levels of recombination and to ensure segregation of homologs. However, homologous pairing also occurs in somatic cells, most regularly in Dipterans such as Drosophila, but also to a lesser extent in other organisms, and it is not known how mitotic and meiotic ...
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