Results 31 to 40 of about 311,541 (282)

Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. [PDF]

PLoS Genetics, 2008
Several meiotic processes ensure faithful chromosome segregation to create haploid gametes. Errors to any one of these processes can lead to zygotic aneuploidy with the potential for developmental abnormalities.
Tom A Hartl, Sarah J Sweeney, Peter J Knepler, Giovanni Bosco   +3 more
doaj   +1 more source

Distribution of chromosome 18 and X centric heterochromatin in the interphase nucleus of cultured human cells [PDF]

, 1990
In situ hybridization of human chromosome 18 and X-specific alphoid DNA-probes was performed in combination with three dimensional (3D) and two dimensional (2D) image analysis to study the interphase distribution of the centric heterochromatin (18c and ...
Agard, Arnoldus, Avivi, Baumann, Belmont, Bennett, Blobel, Borden, Brakenhoff, Brinkley, Comings, Comings, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Devilee, Devilee, Emmerich, Guttenbach, Hadlaczky, Hayflick, Hens, Heslop-Harrison, Hilliker, Hopman, Hopman, Hubert, Johnson, Jovin, Kuhn, Landegent, Langer, Lichter, Lichter, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Mathog, Nederlof, O'Brien, Ochs, Oud, Pinkel, Rappold, Rappold, Rawlins, Rosa, Sachs, Schardin, Schmid, Schroeder, Schwarzacher, Schwarzacher, Stelzer, Vogel, Wijnaendts-van-Resandt, Wollenberg, Yang   +63 more
core   +1 more source

Association of homologous chromosomes during floral development [PDF]

Current Biology, 1997
Reduction in chromosome number and genetic recombination during meiosis require the prior association of homologous chromosomes, and this has been assumed to be a central event in meiosis. Various studies have suggested, however, that while the reduction division of meiosis is a universally conserved process, the pre-meiotic association of homologues ...
Aragón-Alcaide, Luis, Reader, Steve, Beven, Alison, Shaw, Peter, Miller, Terry, Moore, Graham   +5 more
openaire   +2 more sources

Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments [PDF]

, 1982
Unsynchronized cells of an essentially diploid strain of female Chinese hamster cells derived from lung tissue (CHL) were laser-UV-microirradiated (=257 nm) in the nucleus either at its central part or at its periphery.
B Dutrillaux, BA Kihlman, C Cremer, C Cremer, C Cremer, C Cremer, C Wollenberg, C Zorn, C Zorn, C. Cremer, DE Barton, DE Comings, DE Comings, E Therman, F Vogel, FE Fosse Del, H Kato, H. Baumann, HD Hager, JW Gray, K Church, K Nilsson, L Avivi, L Hens, L Hens, L. Hens, LL Deaven, M Ray, M Schmid, M. Kirsch-Volders, S Brenner, T Caspersson, T Cremer, T Cremer, T. Cremer, T. Schneider, Th Boveri, W Sauerbier, Y Moroi   +38 more
core   +1 more source

Human chromosome 19 homologies. [PDF]

Genome Biology, 2001
Gene sequence conservation and lineage-specific evolution are revealed by analysis of homologous sequences in human and mouse.
openaire   +1 more source

HO Endonuclease-Initiated Recombination in Yeast Meiosis Fails To Promote Homologous Centromere Pairing and Is Not Constrained To Utilize the Dmc1 Recombinase

G3: Genes, Genomes, Genetics, 2018
Crossover recombination during meiosis is accompanied by a dramatic chromosome reorganization. In Saccharomyces cerevisiae, the onset of meiotic recombination by the Spo11 transesterase leads to stable pairwise associations between previously ...
Lina Yisehak, Amy J. MacQueen
doaj   +1 more source

On a break with the X: the role of repair of double-stranded DNA breaks in X-linked disease [PDF]

, 2012
The problem of managing free reactive DNA ends in eukaryotic cells has resulted in the development of a number of mechanisms in order to ensure that free ends are rendered non-reactive, or that the double-strand DNA breaks generating the free ends are ...
Cecceroni, Lucia, De Caris, Laura, Tummala, Hemanth   +2 more
core   +4 more sources

Mouse oocytes carrying metacentric Robertsonian chromosomes have fewer crossover sites and higher aneuploidy rates than oocytes carrying acrocentric chromosomes alone

Scientific Reports, 2022
Meiotic homologous recombination during fetal development dictates proper chromosome segregation in adult mammalian oocytes. Successful homologous synapsis and recombination during Meiotic Prophase I (MPI) depends on telomere-led chromosome movement ...
Parinaz Kazemi, Teruko Taketo
doaj   +1 more source

The courtship choreography of homologous chromosomes: timing and mechanisms of DSB-independent pairing

Frontiers in Cell and Developmental Biology, 2023
Meiosis involves deep changes in the spatial organisation and interactions of chromosomes enabling the two primary functions of this process: increasing genetic diversity and reducing ploidy level.
Mireia Solé, Álvaro Pascual, Ester Anton, Joan Blanco, Zaida Sarrate   +4 more
doaj   +1 more source

PAR-TERRA directs homologous sex chromosome pairing [PDF]

Nature Structural & Molecular Biology, 2017
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a required interaction between the X-inactivation center (Xic) and the telomere in mouse embryonic stem (ES ...
Hsueh-Ping Chu, John E Froberg, Barry Kesner, Hyun Jung Oh, Fei Ji, Ruslan Sadreyev, Stefan F Pinter, Jeannie T Lee   +7 more
openaire   +3 more sources