Results 31 to 40 of about 1,025,592 (331)

A recurrent translocation is mediated by homologous recombination between HERV-H elements

Molecular Cytogenetics, 2012
Background Chromosome rearrangements are caused by many mutational mechanisms; of these, recurrent rearrangements can be particularly informative for teasing apart DNA sequence-specific factors.
Hermetz Karen E, Surti Urvashi, Cody Jannine D, Rudd M Katharine   +3 more
doaj   +1 more source

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination

Frontiers in Plant Science, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio, Heïdi Serra, Pierre Sourdille, James D. Higgins   +3 more
doaj   +1 more source

Improved reconstruction and comparative analysis of chromosome 12 to rectify Mis-assemblies in Gossypium arboreum

BMC Genomics, 2020
Background Genome sequencing technologies have been improved at an exponential pace but precise chromosome-scale genome assembly still remains a great challenge. The draft genome of cultivated G.
Javaria Ashraf, Dongyun Zuo, Hailiang Cheng, Waqas Malik, Qiaolian Wang, Youping Zhang, Muhammad Ali Abid, Qiuhong Yang, Xiaoxu Feng, John Z. Yu, Guoli Song   +10 more
doaj   +1 more source

Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. [PDF]

PLoS Genetics, 2008
Several meiotic processes ensure faithful chromosome segregation to create haploid gametes. Errors to any one of these processes can lead to zygotic aneuploidy with the potential for developmental abnormalities.
Tom A Hartl, Sarah J Sweeney, Peter J Knepler, Giovanni Bosco   +3 more
doaj   +1 more source

Association of homologous chromosomes during floral development [PDF]

Current Biology, 1997
Reduction in chromosome number and genetic recombination during meiosis require the prior association of homologous chromosomes, and this has been assumed to be a central event in meiosis. Various studies have suggested, however, that while the reduction division of meiosis is a universally conserved process, the pre-meiotic association of homologues ...
Graham Moore, Luis Aragón-Alcaide, Peter Shaw, T. E. Miller, S. M. Reader, Alison F. Beven   +5 more
openaire   +3 more sources

HO Endonuclease-Initiated Recombination in Yeast Meiosis Fails To Promote Homologous Centromere Pairing and Is Not Constrained To Utilize the Dmc1 Recombinase

G3: Genes, Genomes, Genetics, 2018
Crossover recombination during meiosis is accompanied by a dramatic chromosome reorganization. In Saccharomyces cerevisiae, the onset of meiotic recombination by the Spo11 transesterase leads to stable pairwise associations between previously ...
Lina Yisehak, Amy J. MacQueen
doaj   +1 more source

The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.

Annual Review of Biochemistry, 2019
Mutations in the BRCA1 and BRCA2 genes predispose afflicted individuals to breast, ovarian, and other cancers. The BRCA-encoded products form complexes with other tumor suppressor proteins and with the recombinase enzyme RAD51 to mediate chromosome ...
Weixing Zhao, C. Wiese, Youngho Kwon, R. Hromas, P. Sung   +4 more
semanticscholar   +1 more source

Chromosome-associated RNA–protein complexes promote pairing of homologous chromosomes during meiosis in Schizosaccharomyces pombe

Nature Communications, 2019
Pairing of homologous chromosomes in meiosis is essential for sexual reproduction. We have previously demonstrated that the fission yeast sme2 RNA, a meiosis-specific long noncoding RNA (lncRNA), accumulates at the sme2 chromosomal loci and mediates ...
Da‐Qiao Ding, Kasumi Okamasa, Y. Katou, Eriko Oya, J. Nakayama, Y. Chikashige, K. Shirahige, T. Haraguchi, Y. Hiraoka   +8 more
semanticscholar   +1 more source

Mouse oocytes carrying metacentric Robertsonian chromosomes have fewer crossover sites and higher aneuploidy rates than oocytes carrying acrocentric chromosomes alone

Scientific Reports, 2022
Meiotic homologous recombination during fetal development dictates proper chromosome segregation in adult mammalian oocytes. Successful homologous synapsis and recombination during Meiotic Prophase I (MPI) depends on telomere-led chromosome movement ...
Parinaz Kazemi, Teruko Taketo
doaj   +1 more source

Human chromosome 19 homologies. [PDF]

Genome Biology, 2001
Gene sequence conservation and lineage-specific evolution are revealed by analysis of homologous sequences in human and mouse.
openaire   +2 more sources