Results 51 to 60 of about 1,161,690 (369)

Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis. [PDF]

open access: yesPLoS Genetics, 2013
Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of recombination, provide the physical link that holds the homologs together as a pair, facilitating ...
Michel F Guiraldelli   +4 more
doaj   +1 more source

PAR-TERRA directs homologous sex chromosome pairing

open access: yesNature Structural &Molecular Biology, 2017
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known.
H. Chu   +7 more
semanticscholar   +1 more source

Association of homologous chromosomes during floral development [PDF]

open access: yesCurrent Biology, 1997
Reduction in chromosome number and genetic recombination during meiosis require the prior association of homologous chromosomes, and this has been assumed to be a central event in meiosis. Various studies have suggested, however, that while the reduction division of meiosis is a universally conserved process, the pre-meiotic association of homologues ...
Aragón-Alcaide, Luis   +5 more
openaire   +2 more sources

Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes

open access: yesMolecular Biology of the Cell, 2013
Oocyte-specific deletion of Cdc42 has little effect on meiotic spindle organization and migration to the cortex but inhibits polar body emission, although homologous chromosome segregation occurs.
Zhenbo Wang   +11 more
semanticscholar   +1 more source

Phylogenetic inferences of Atelinae (Platyrrhini) based on multi-directional chromosome painting in Brachyteles arachnoides, Ateles paniscus paniscus and Ateles b. marginatus [PDF]

open access: yes, 2005
We performed multi-directional chromosome painting in a comparative cytogenetic study of the three Atelinae species Brachyteles arachnoides, Ateles paniscus paniscus and Ateles belzebuth marginatus, in order to reconstruct phylogenetic relationships ...
C. Nagamachi   +17 more
core   +1 more source

Genetic Requirements for Intra-Chromosomal Deletions [PDF]

open access: yes, 2020
Chromosomal deletions are one of the most dangerous types of DNA damage and often arise as a result of inappropriately repaired DNA double strand breaks (DSB).
McPherson, Matthew
core  

Agent-based modeling of nuclear chromosome ensembles identifies determinants of homolog pairing during meiosis.

open access: yesPLoS Computational Biology
During meiosis, pairing of homologous chromosomes (homologs) ensures the formation of haploid gametes from diploid precursor cells, a prerequisite for sexual reproduction.
Ariana Chriss   +2 more
doaj   +1 more source

Extensive DNA end processing by exo1 and sgs1 inhibits break-induced replication.

open access: yesPLoS Genetics, 2010
Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH).
Vanessa A Marrero, Lorraine S Symington
doaj   +1 more source

The origin of human chromosome 2 analyzed by comparative chromosome mapping with a DNA microlibrary [PDF]

open access: yes, 1994
Fluorescencein situ hybridization (FISH) of microlibraries established from distinct chromosome subregions can test the evolutionary conservation of chromosome bands as well as chromosomal rearrangements that occurred during primate evolution and will ...
A Baldini   +32 more
core   +1 more source

Optimal Haplotype Assembly from High-Throughput Mate-Pair Reads

open access: yes, 2015
Humans have $23$ pairs of homologous chromosomes. The homologous pairs are almost identical pairs of chromosomes. For the most part, differences in homologous chromosome occur at certain documented positions called single nucleotide polymorphisms (SNPs).
Kamath, Govinda M.   +2 more
core   +1 more source

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