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The Origin of a New Sex Chromosome by Introgression between Two Stickleback Fishes. [PDF]
Introgression is increasingly recognized as a source of genetic diversity that fuels adaptation. Its role in the evolution of sex chromosomes, however, is not well known. Here, we confirm the hypothesis that the Y chromosome in the ninespine stickleback,
Abbott+78 more
core +1 more source
Oocyte-specific deletion of Cdc42 has little effect on meiotic spindle organization and migration to the cortex but inhibits polar body emission, although homologous chromosome segregation occurs.
Zhenbo Wang+11 more
semanticscholar +1 more source
Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis. [PDF]
Faithful chromosome segregation during meiosis requires that homologous chromosomes associate and recombine. Chiasmata, the cytological manifestation of recombination, provide the physical link that holds the homologs together as a pair, facilitating ...
Michel F Guiraldelli+4 more
doaj +1 more source
Securin Is Not Required for Chromosomal Stability in Human Cells [PDF]
Abnormalities of chromosome number are frequently observed in cancers. The mechanisms regulating chromosome segregation in human cells are therefore of great interest.
Azofeifa+32 more
core +4 more sources
The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis.
COM1/SAE2 is a highly conserved gene from yeast to higher eukaryotes. Its orthologs, known to cooperate with the MRX complex (Mre11/Rad50/Xrs2), are required for meiotic DNA double-strand break (DSB) ends resection and specific mitotic DSB repair events.
Jianhui Ji+6 more
semanticscholar +1 more source
GenomeFingerprinter and universal genome fingerprint analysis for systematic comparative genomics [PDF]
How to compare whole genome sequences at large scale has not been achieved via conventional methods based on pair-wisely base-to-base comparison; nevertheless, no attention was paid to handle in-one-sitting a number of genomes crossing genetic category ...
Ai, Hannan+3 more
core +7 more sources
Distance between homologous chromosomes results from chromosome positioning constraints [PDF]
The organization of chromosomes is important for various biological processes and is involved in the formation of rearrangements often observed in cancer. In mammals, chromosomes are organized in territories that are radially positioned in the nucleus. However, it remains unclear whether chromosomes are organized relative to each other.
Heride, Claire+7 more
openaire +5 more sources
Chromosome segregation in plant meiosis [PDF]
Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
De Storme, Nico+4 more
core +2 more sources
Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements [PDF]
Replication fork inactivation can be overcome by homologous recombination, but this can cause gross chromosomal rearrangements that subsequently missegregate at mitosis, driving further chromosome instability.
A Janssen+39 more
core +1 more source
During meiosis, pairing of homologous chromosomes (homologs) ensures the formation of haploid gametes from diploid precursor cells, a prerequisite for sexual reproduction.
Ariana Chriss+2 more
doaj +1 more source