Control of homologous chromosome division in the mammalian oocyte [PDF]
Molecular Human Reproduction, 2009 Homologous chromosomes are segregated during the first meiotic division (meiosis I). Unfortunately, human oocytes are particularly susceptible to mis-segregation errors, so generating aneuploid, often non-viable, embryos. Here we review the cell biology of meiosis I and how homolog disjunction is regulated for mammalian oocytes.
Holt, Janet E., Jones, Keith T.
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Gene doctoring: a method for recombineering in laboratory and pathogenic Escherichia coli strains [PDF]
, 2009 Background: Homologous recombination mediated by the lambda-Red genes is a common method for making chromosomal modifications in Escherichia coli.
Bingle, Lewis EH +6 more
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The Attraction between Homologous Chromosomes [PDF]
Nature, 1925 IT has been shown that the chromosomes of Datura (American Naturalist, vol. 56, pp. 339–346, 1922), Hyacinthus (Genetics, vol. 10, pp. 59–71, 1925) and Uvularia (Journal of Genetics, in press), for example, are combined side by side, and end to end, at the reduction division.
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Optimal Haplotype Assembly from High-Throughput Mate-Pair Reads
, 2015 Humans have $23$ pairs of homologous chromosomes. The homologous pairs are almost identical pairs of chromosomes. For the most part, differences in homologous chromosome occur at certain documented positions called single nucleotide polymorphisms (SNPs).
Kamath, Govinda M. +2 more
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Multidirectional chromosome painting substantiates the occurrence of extensive genomic reshuffling within Accipitriformes. [PDF]
, 2015 BACKGROUND: Previous cross-species painting studies with probes from chicken (Gallus gallus) chromosomes 1-10 and a paint pool of nineteen microchromosomes have revealed that the drastic karyotypic reorganization in Accipitridae is due to extensive ...
Beiyuan Fu +10 more
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Which one is the real matchmaker for the pair?
Asian Journal of Andrology, 2014 A fundamental question for meiosis is how homologous chromosomes (homologs) find each other and pair together to ensure homologous recombination and segregation.
Chunsheng Han
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Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. [PDF]
PLoS Genetics, 2013 Cohesin subunit SMC1β is specific and essential for meiosis. Previous studies showed functions of SMC1β in determining the axis-loop structure of synaptonemal complexes (SCs), in providing sister chromatid cohesion (SCC) in metaphase I and thereafter, in
Uddipta Biswas +6 more
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Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla [PDF]
, 1992 The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined ...
Bigoni, F. +5 more
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On the role of homologous sequences in chromosomal rearrangements. [PDF]
Genes & Development, 1988 Deletions and other chromosomal rearrangements can be generated by recombination between repeated sequences. It has been shown in a number of systems that the probability of exchange or gene conversion decreases with increasing distance between repeats.
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Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]
, 2006 In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad +102 more
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