Results 61 to 70 of about 611,533 (294)

Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Darren K Griffin, Foster, H, Bridger Joanna M, Bridger, JM, Foster Helen A, Griffin, DK, Foster, Helen A., Bridger, Joanna M., Joanna M Bridger, Helen A Foster, Griffin Darren K, Griffin, Darren K.   +11 more
core   +1 more source

Kif11-haploinsufficient oocytes reveal spatially differential requirements for chromosome biorientation

EMBO Reports
Bipolar spindle assembly and chromosome biorientation are prerequisites for chromosome segregation during cell division. The kinesin motor KIF11 (also widely known as Eg5) drives spindle bipolarization by sliding antiparallel microtubules bidirectionally,
Tappei Mishina, Aurélien Courtois, Shuhei Yoshida, Kohei Asai, Hiroshi Kiyonari, Tomoya S Kitajima   +5 more
doaj   +1 more source

Finding the Correct Partner: The Meiotic Courtship

Scientifica, 2012
Homologous chromosomes are usually separated at the entrance of meiosis; how they become paired is one of the outstanding mysteries of the meiotic process.
Tomás Naranjo
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Homologous recombination, sister chromatid cohesion, and chromosome condensation in mammalian meiosis [PDF]

, 2002
In the life cycle of sexually reproducing eukaryotes, haploid and diploid generations of cells alternate. Two types of cell division occur in such a life cycle: mitosis and meiosis. They are compared in chapter 1 .
Eijpe, M.
core  

Identification of novel Y chromosome encoded transcripts by testis transcriptome analysis of mice with deletions of the Y chromosome long arm. [PDF]

, 2005
BACKGROUND The male-specific region of the mouse Y chromosome long arm (MSYq) is comprised largely of repeated DNA, including multiple copies of the spermatid-expressed Ssty gene family.
Ojarikre, Obah A., Obah A Ojarikre, Loveland, Kate, Clemente, Emily J., Reynard, Louise, Affara, Nabeel A., Affara, Nabeel, Peter Ellis, Mahadevaiah, Shantha K., Ellis, Peter J.I., Mahadevaiah, Shantha, Ball, Penny A.F., Peter JI Ellis, Burgoyne, P, Shantha K Mahadevaiah, Nabeel A Affara, Ojarikre, Obah, Loveland, Kate L., Burgoyne, Paul S., Louise Reynard, Kate L Loveland, Aminata Touré, Clemente, Emily, Touré, Aminata, Emily J Clemente, Ball, Penny, Penny AF Ball, Ellis, Peter, Paul S Burgoyne   +28 more
core   +7 more sources

Data_sheet_1_FIGNL1 Inhibits Non-homologous Chromosome Association and Crossover Formation.pdf

, 2022
Meiotic crossovers (COs) not only generate genetic diversity but also ensure the accuracy of homologous chromosome segregation. Here, we identified FIGNL1 as a new inhibitor for extra crossover formation in rice.
Shuying Yang (309302), Yi Shen (152956), Yiwei Cao (9089167), Hengxiu Yu (573567), Yafei Li (184478), Zhukuan Cheng (45762), Guijie Du (5954015), Ding Tang (152954), Chao Zhang (51048)   +8 more
core   +1 more source

Functional characterization of the Caenorhabditis elegans gene fcd-2 during meiosis and in maintenance of genomic stability [PDF]

, 2009
Fanconi anemia (FA) is a complex cancer susceptibility disorder associated with defects in the repair of DNA interstrand cross-links (ICLs) resulting in occasional developmental defects and in ICL hypersensitivity of patient cells, yet the precise role ...
Silva, Nicola
core   +1 more source

Chromosome Manipulation for Plant Breeding Purposes

Agronomy, 2020
The transfer of genetic variability from related species into crops has been a main objective for decades in breeding programs. Breeders have used interspecific genetic crosses and alien introgression lines to achieve this goal, but the success is always
Pilar Prieto
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source