Results 121 to 130 of about 2,294,281 (319)

Which way up? Recognition of homologous DNA segments in parallel and antiparallel alignment

open access: yes, 2014
Homologous gene shuffling between DNA promotes genetic diversity and is an important pathway for DNA repair. For this to occur, homologous genes need to find and recognize each other.
Aaron Wynveen   +6 more
core   +1 more source

The G-sequence and the ω-homology of a CW-pair

open access: yesTopology and its Applications, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lee, Kee Young, Woo, Moo Ha
openaire   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange

open access: yesNucleic Acids Research, 2009
RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks.
Takako Ishida   +8 more
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities

open access: yesNucleic Acids Research, 2009
RAD51, a eukaryotic recombinase, catalyzes homologous-pairing and strand-exchange reactions, which are essential steps in homologous recombination and recombinational repair of double strand breaks.
Yuichi Morozumi   +3 more
semanticscholar   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

TurboFold: Iterative probabilistic estimation of secondary structures for multiple RNA sequences

open access: yesBMC Bioinformatics, 2011
Background The prediction of secondary structure, i.e. the set of canonical base pairs between nucleotides, is a first step in developing an understanding of the function of an RNA sequence.
Sharma Gaurav   +2 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Cohomology rings, Rochlin function, linking pairing and the Goussarov--Habiro theory of three--manifolds

open access: yes, 2003
We prove that two closed oriented 3-manifolds have isomorphic quintuplets (homology, space of spin structures, linking pairing, cohomology rings, Rochlin function) if, and only if, they belong to the same class of a certain surgery equivalence relation ...
Gwénaël Massuyeau   +6 more
core   +3 more sources

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