Results 191 to 200 of about 345,396 (332)

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

Advanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang, Jie‐Mei Zhao, Chuan‐Yu Xiang, Yi‐Wen Ma, Hong‐Peng Lei, Yu‐Ying Shi, Shun Zhou, Xiaofei Zeng, Jinsong Chen, Fei Liu, Benhe Zeng, Rui Song, Ye Hu, Feng Zhang, Xiang Liu, Wen‐Xiang Li, Gui‐Tang Wang, Ivan Jakovlić   +17 more
wiley   +1 more source

Pan-cancer analysis of homologous recombination deficiency and homologous recombination repair-associated gene alterations in solid tumors from a large Asian cohort. [PDF]

BMC Cancer
Ren L, Yao R, Hou T, Liu C, Zhao F, Chen X, Zhang Z, Huang Y.   +7 more
europepmc   +1 more source

Rapid assay for extrachromosomal homologous recombination in monkey cells.

, 1985
Jeffrey E. Rubnitz, Suresh Subramani
openalex   +1 more source

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

The distinct landscape of tumor immune microenvironment in homologous recombination deficient cancers. [PDF]

Biomark Res
Xu Q, Wen Y, Huang T, Li H, Liu X, Shi SN, Gong W, Mills GB, Ma D, Gao Q, Fang Y.   +10 more
europepmc   +1 more source

Mutations and homologous recombination induced in mammalian cells by metabolites of benzo[a]pyrene and 1-nitropyrene.

, 1987
Vincent Maher, J D Patton, Jia‐Ling Yang, Y Y Wang, Li Yang, A.E. Aust, Nitai P. Bhattacharyya, J J McCormick   +7 more
openalex   +1 more source

A mitochondrial retroplasmid integrates into mitochondrial DNA by a novel mechanism involving the synthesis of a hybrid cDNA and homologous recombination. [PDF]

, 1994
Chia-Chien Chiang, John C. Kennell, Leslie A. Wanner, Alan M. Lambowitz   +3 more
openalex   +1 more source

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, EarlyView.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

Phosphorylation of RNF213 by ATM-mediated ubiquitination of RPA1 regulates homologous recombination repair and chemosensitivity. [PDF]

Cell Death Dis
Hu D, Wu W, Wu C, Li J, Ruan B, Cheng H, Jiang Y, Wang Y, Song Z.   +8 more
europepmc   +1 more source

Extrachromosomal homologous DNA recombination in plant cells is fast and is not affected by CpG methylation. [PDF]

, 1992
Holger Puchta, Serge Kocher, Barbara Höhn   +2 more
openalex   +1 more source