Results 211 to 220 of about 769,180 (373)
Approaches to repurposing reverse transcriptase antivirals in cancer
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head+2 more
wiley +1 more source
Pan-cancer analysis of homologous recombination deficiency and homologous recombination repair-associated gene alterations in solid tumors from a large Asian cohort. [PDF]
Ren L+7 more
europepmc +1 more source
Reversion of Q beta RNA phage mutants by homologous RNA recombination [PDF]
Kampan Palasingam, Patrick N. Shaklee
openalex +1 more source
Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley +1 more source
The prognostic and predictive value of homologous recombination deficiency in gastrointestinal cancer. [PDF]
Jiang B+10 more
europepmc +1 more source
When numbers matter: Rethinking the role of gene duplication on short evolutionary timescales
American Journal of Botany, EarlyView.
Freja Lindstedt+2 more
wiley +1 more source
ABSTRACT Cyanobacteria are photoautotrophic microorganisms with significant applications in biotechnology. Although many cyanobacteria, including Picosynechococcus sp. (formerly called Synechococcus sp.) PCC 11901 (Picosynechococcus) and Synechocystis sp.
Cecilia Salvagnini+7 more
wiley +1 more source
Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source