Results 231 to 240 of about 773,827 (377)

Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins.

Cold Spring Harbor Perspectives in Biology, 2015
Rohit Prakash, Yu Zhang, Weiran Feng, M. Jasin   +3 more
semanticscholar   +1 more source

Comparison of homologous recombination frequencies in somatic cells of petunia and tobacco suggest two distinct recombination pathways [PDF]

, 1992
Peter Engels, Peter Meyer
openalex   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination. [PDF]

Nat Commun
Deveryshetty J, Mistry A, Pangeni S, Ghoneim M, Tokmina-Lukaszewska M, Gore SK, Liu J, Kaushik V, Karunakaran S, Taddei A, Heyer WD, Ha T, Bothner B, Antony E.   +13 more
europepmc   +1 more source

Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer.

Cancer Discovery, 2015
P. Konstantinopoulos, Raphael Ceccaldi, G. Shapiro, A. D’Andrea   +3 more
semanticscholar   +1 more source

Adenovirus homologous recombination does not require expression of the immediate-early E1a gene [PDF]

, 1991
Lisa H. Epstein, C.S. Young
openalex   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

CG>TG mutation frequency as negative predictor of homologous recombination deficiency in ovarian and breast cancer. [PDF]

Commun Biol
Romanovsky E, Menzel M, Kluck K, Beck S, Ball M, Schirmacher P, Kazdal D, Stenzinger A, Budczies J.   +8 more
europepmc   +1 more source

Distribution of exchanges upon homologous recombination of exogenous DNA in Xenopus laevis oocytes.

, 1994
Dana Carroll, Chris W. Lehman, S Jeong-Yu, Paul R. Dohrmann, Renee J. Dawson, Jonathan K. Trautman   +5 more
openalex   +2 more sources

Homologous Recombination in Human Mitochondria?

The American Journal of Human Genetics, 1997
openaire   +3 more sources