Results 241 to 250 of about 766,679 (374)

The uraA locus and homologous recombination in Mycobacterium bovis BCG

, 1993
Anna Aldovini, Robert N. Husson, R A Young   +2 more
openalex   +1 more source

Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

Nature Biotechnology, 2013
Jian-Feng Li, J. Norville, John D Aach, M. McCormack, Dandan Zhang, Jenifer Bush, G. Church, J. Sheen   +7 more
semanticscholar   +1 more source

ASPM Induces Radiotherapy Resistance by Disrupting Microtubule Stability Leading to Chromosome Malsegregation in Non‐Small Cell Lung Cancer

Exploration, EarlyView.
Abnormal spindle‐like microcephaly‐associated protein helps radiotherapy resistant cells to evade spindle checkpoint surveillance and complete cell division after irradiation through destruction of microtubule stability, with subsequent increases in chromosome mis‐segregation and deteriorating chromosomal stability during mitosis to promote ...
Tao Zhong, Ning Liu, Juan Wang, Songbo Xie, Lisheng Liu, Minglei Wang, Fei Wu, Xiaozheng Chen, Changyan Xiao, Xiaoxiao Gongye, Meng Wu, Liewei Wen, Jinming Yu, Dawei Chen   +13 more
wiley   +1 more source

Adenovirus homologous recombination does not require expression of the immediate-early E1a gene [PDF]

, 1991
Lisa H. Epstein, C.S. Young
openalex   +1 more source

Repression of BET activity sensitizes homologous recombination–proficient cancers to PARP inhibition

Science Translational Medicine, 2017
Lu Yang, Youyou Zhang, Weiwei Shan, Zhongyi Hu, Jiao Yuan, Jingjiang Pi, Yueying Wang, L. Fan, Zhaoqing Tang, Chunsheng Li, Xiaowen Hu, J. Tanyi, Yi Fan, Qihong Huang, K. Montone, C. Dang, Lin Zhang   +16 more
semanticscholar   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

Autophagy induction enhances homologous recombination-associated CRISPR-Cas9 gene editing. [PDF]

Nucleic Acids Res
Nam HJ, Han JH, Yu J, Cho CS, Kim D, Kim YE, Kim MJ, Kim JH, Jo DH, Bae S.   +9 more
europepmc   +1 more source

Self‐Emulsifying Biocatalysis Based on an Amphipathic Protein BslA‐Modified Esterase Functioning as a Fine‐Tuned System for Oil Hydrolysis

Food Bioengineering, EarlyView.
BslA is a promising tool to create an robust self‐emulsifying biocatalysis platform by reducing the droplet sizes of emulsion and improving its stability. It could guarantee the efficient hydrolysis of astaxanthin esters catalyzed by Est3‐14 without extra emusifier, increasing the yield of free astaxanthin to 184 μg·mL−1.
Xiaoxuan Yao, Kunpeng Gao, Hao Dong, Qian Sun, Jingyuan Liu, Yang Hu, Jianan Sun, Xiangzhao Mao   +7 more
wiley   +1 more source

Extensive homologous recombination safeguards oocyte genome integrity in mammals. [PDF]

Nucleic Acids Res
Cao H, Qiu C, Fang A, Shang J, Xu W, He L, Duan X, Zhang Q, Yu C.   +8 more
europepmc   +1 more source

Comments on important genetic topics from papers in other journals: Prospects for homologous recombination in human gene therapy [PDF]

, 1992
J C K Barber
openalex   +1 more source