Results 261 to 270 of about 651,783 (359)

Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines. [PDF]

open access: yesCancer Res Commun
Dodson AE   +11 more
europepmc   +1 more source

Mechanisms of enhancer‐driven oncogene activation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend   +2 more
wiley   +1 more source

Homologous recombination in Leishmania enriettii.

open access: green, 1991
James F. Tobin   +2 more
openalex   +1 more source

Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.

open access: yesMolecules and Cells, 2017
S. Sivanand   +14 more
semanticscholar   +1 more source

Nationwide implementation and evaluation of the Tumor‐First workflow for genetic testing in ovarian carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The Tumor‐First workflow is a genetic testing strategy developed to detect pathogenic variants in ovarian cancer risk genes. Recently implemented in the Netherlands, this workflow aims to stratify germline testing while providing information on the effectiveness of PARP inhibitor therapy.
Vera M. Witjes   +50 more
wiley   +1 more source

Prp19/CDC5L promotes gastric cancer via activation of the MAPK pathway-mediated homologous recombination. [PDF]

open access: yesInt J Biol Sci
Qiu S   +11 more
europepmc   +1 more source

Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini   +18 more
wiley   +1 more source

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