Results 261 to 270 of about 766,679 (374)

Rescue of end fragments of yeast artificial chromosomes by homologous recombination in yeast

, 1991
Gary Hermanson, Merl F. Hoekstra, David L. McElligott, Glen A. Evans   +3 more
openalex   +1 more source

Construction of specific cosmids from YACs by homologous recombination in yeast [PDF]

, 1995
Laura B. K. Herzing, Alan Ashworth
openalex   +1 more source

SLFN11 inhibits checkpoint maintenance and homologous recombination repair

EMBO Reports, 2016
Yanhua Mu, Jiangman Lou, Mrinal Srivastava, Bin Zhao, Xin-Hua Feng, Ting Liu, Junjie Chen, Jun Huang   +7 more
semanticscholar   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Nuclear-Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance. [PDF]

Adv Sci (Weinh)
Liu H, Feng J, Pan T, Zhang P, Ye L, Jiang Z, Zhou Z, Mao Q, Li J, Yang X, Gao P, Huang, Zhang H.   +12 more
europepmc   +1 more source

The role of protein-protein interactions in the assembly of the presynaptic filament for T4 homologous recombination.

, 1993
Hong Jiang, David Giedroc, Thomas Kodadek   +2 more
openalex   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

The impact of homologous recombination deficiency on the prognosis of epithelial ovarian cancer. [PDF]

Clin Transl Med
Su H, Wang Y, Chao X, Wu H, You Y, Zhao S, Wang F, Sun B, Zhang Z, Wu M, Zhao Z, Li L.   +11 more
europepmc   +1 more source

Multiple origins of the human glycophorin Sta gene. Identification of hot spots for independent unequal homologous recombinations.

, 1991
Chi‐Hsiang Huang, Olga O. Blumenfeld
openalex   +1 more source

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

International Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart, Lars Tögel, Maria Giulia Carta, Philip Hetzner, Lina Helbig, Charlotte Zaglas, Maria Ziegler, Robert Stöhr, Annett Hölsken, Juliane Hoyer, Fulvia Ferrazzi, Clemens Neufert, Sebastian Lettmaier, Marianne Pavel, Henriette Golcher, Sarina K. Mueller, Florian Fuchs, Carla E. Schulmeyer, Matthias W. Beckmann, Bernd Wullich, Abbas Agaimy, Andre Reis, Arndt Hartmann, Norbert Meidenbauer, Silvia Spoerl, Florian Haller, Evgeny A. Moskalev   +26 more
wiley   +1 more source