Results 261 to 270 of about 651,783 (359)
Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines. [PDF]
Dodson AE+11 more
europepmc +1 more source
Homologous recombination occurs in a distinct retroviral subpopulation and exhibits high negative interference [PDF]
Wei Hu+3 more
openalex +1 more source
Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend+2 more
wiley +1 more source
Homologous recombination in Leishmania enriettii.
James F. Tobin+2 more
openalex +1 more source
Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.
S. Sivanand+14 more
semanticscholar +1 more source
What's New? The Tumor‐First workflow is a genetic testing strategy developed to detect pathogenic variants in ovarian cancer risk genes. Recently implemented in the Netherlands, this workflow aims to stratify germline testing while providing information on the effectiveness of PARP inhibitor therapy.
Vera M. Witjes+50 more
wiley +1 more source
Prp19/CDC5L promotes gastric cancer via activation of the MAPK pathway-mediated homologous recombination. [PDF]
Qiu S+11 more
europepmc +1 more source
Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients
What's New? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini+18 more
wiley +1 more source
Repression of PFKFB3 sensitizes ovarian cancer to PARP inhibitors by impairing homologous recombination repair. [PDF]
Xiao Y+5 more
europepmc +1 more source