Multiomics analysis of homologous recombination deficiency across cancer types. [PDF]
Dong L+8 more
europepmc +1 more source
Synthetic biology for medical biomaterials
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu+4 more
wiley +1 more source
Optimizing Yeast Homologous Recombination for Splicing Large Coronavirus Genome Fragments. [PDF]
Xiong G+9 more
europepmc +1 more source
Distribution of exchanges upon homologous recombination of exogenous DNA in Xenopus laevis oocytes.
Dana Carroll+5 more
openalex +2 more sources
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li+5 more
wiley +1 more source
Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy. [PDF]
Wang Y+17 more
europepmc +1 more source
Coupling of Homologous Recombination and the Checkpoint by ATR.
R. Buisson+11 more
semanticscholar +1 more source
Cold atmospheric plasma combined with nanoparticles in cancer therapy
Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang+7 more
wiley +1 more source
The role of human Shu complex in ATP-dependent regulation of RAD51 filaments during homologous recombination-associated DNA damage response. [PDF]
Chu SSH, Xing G, Ling H.
europepmc +1 more source
[An homologous recombination strategy to directly clone mammalian telomeres]. Progress report
Geoffrey M. Wahl
openalex +2 more sources